这些核激素受体由其配体(激活物)激活后，通过偶联特异的反应元件来调控多种靶基因的表达。
After activation by ligand as is the case with nuclear receptors, PPARs binds to a specific element in the promoter region of target genes.
目的动态观察CD44及其配体骨调素(opn)在大鼠酒精性肝纤维化形成过程巾的表达并初步探讨其作用。
Objective To investigate dynamic expression of CD44 and its ligand osteopontin (OPN) on the formation of alcoholic hepatic fibrosis.
其配体是唾液酸化的路易斯寡糖或类似结构的分子，在中性粒细胞、嗜酸性粒细胞和正常骨髓前体细胞上大量表达。
Its ligand is sialyl Louis oligosaccharides or similar molecular structure, and expresses in neutrophils, eosinophils and normal bone marrow precursor cells.
多巴胺受体根据其对腺苷酸环化酶活力的不同影响及具有专一性配体分为D 1样和D2样两型。
Dopamine receptors are classified into D1 and D2 types based upon their effects on adenylate cyclase activity and their specific ligands.
对足月胎盘进行体外培养时，发现其表面的TLR - 2或者TLR - 4在与配体结合后能使胎盘产生IL - 6和IL - 8 (19)。
Explants from term placenta have been shown to produce IL-6 and IL-8 following ligation of TLR-2 or TLR-4 (19).
本文提出了医院绩效工资考核分配体系的设计原则，构建了基本框架，并对其预期效果进行了分析。
This paper discussed the principle of design, the frame and the expected effect about the appraisal and distribution system of the performance-related-pay in hospital.
该文针对火炮炮尾炮闩机构提出了对其进行装配体有限元分析的方法和建模原理。
The principle and methodology of assembly level finite element modeling and analysis of gun breech mechanism were put forward in this paper.
自然杀伤细胞通过其表达的不同类型的受体选择性识别细胞表面的相应配体，提供自然杀伤细胞反应的自我调节信号。
Different types of receptors expressed by natural killer (NK) cells may selectively recognize their specific ligands on some other cells and provide self-regulatory signals to control NK responses.
于是，我们和其合作来深入研究该类配体的不对称催化机制和功能，得到了如下有意义的结果。
Thus we cooperate to study the function and mechanism of this catalyst in the asymmetric borane reduction reaction, and the following results are obtained.
肝组织GR采用放射性配体结合分析法测定其最大结合容量以及用免疫印迹法测定其蛋白含量。
Maximal binding volume of glucocorticoid receptor (GR) in hepatic tissue was assayed by radio-ligand binding assay and protein content was assayed by Western blot.
双功能有机配体2,4,6 -吡啶三甲酸、其水溶性稀土荧光标记材料及其制备方法。
Bifunctional organic ligand 2, 4, 6-pyridine tricarboxylic acid, water-soluble rare-earth fluorescence labeling material and preparation method thereof.
TGF配体虽然在早期肿瘤中作为肿瘤抑制基因发挥作用，但其在进展期肿瘤中却变成有效的促转移因子。
TGF ligands act as tumor suppressors in early stage tumors but are paradoxically diverted into potent prometastatic factors in advanced cancers.
近年来，含氮三角架配体由于其多配位点、半刚性及易合成等特点，引起了人们的广泛兴趣。
In the last few years, the tripodal ligands bearing nitrogen atoms have drown much attention because of their polydentate, flexility and ease to synthesize.
其结果显示了配体的质子化和金属配合物的形成受到焓变化的控制。
The result shows that both the protonation of the ligands and the formation of metal complexes are controlled by the change of enthalpy.
结果推定了配合物具有草酸根桥联结构，其抗菌活性优于桥配体。
And the results show that antibacterial activities of the heterotetranuclear complexes are superior to the complex ligand.
其方法的核心是对受体-配体相互作用的研究。
The kernel of the methodology focus on the studies of the interactions between receptor and ligand.
芳基柔性二齿配体的配位构型多变，使得其金属配合物的结构丰富多彩。
Self assembly of aryl group containing flexible bidentate ligands with metal ions gives rise to many types of novel structures because of their variable coordination modes.
合成了三种与咪唑配体键合的新型载体，并通过其与四苯基卟啉铁和卟啉锰配位得到了改性的负载金属卟啉催化剂。
Three new supporters bonded with ligand imidazole have been prepared. Modified catalysts of metalloporphyrins have been obtained by coordination of TPPFeCl or TPPMnCl with supporters.
其方法的核心是对受体-配体相互作用的研究。
The kernel of the methodology focuses on the studies of the interactions between receptor and ligand.
PR A和PR B都是配体激活，但其激活靶基因转录的相对能力是不同的(3,4)。
Both PR-A and PR-B are ligand activated, but differ in their relative ability to activate target gene transcription (3, 4).
制备骨肿瘤治疗或诊断用的放射性药物的药盒制备方法是将至少一个放射性核素与一个配体或其药用盐反应，形成络合物。
The preparation process is to make at least one radio active nuclide and one ligand or its medicinal salt react to form complex.
本发明涉及新的水溶性纤维素衍生物，其包含能够与多价金属离子形成配合物的配体。
The invention relates to novel water-soluble cellulose derivatives comprising a ligand capable of forming a complex with a polyvalent metal ion.
PEM法为优化固定在纳米颗粒的表面上的配体提供了一种有用的工具，并可能在生物活性测量不便时显示其良好的优势。
The PEM method provides a useful tool to optimize ligand immobilization at the surface of nanoparticles, and may be advantageous when biological activity measurements are not convenient.
由于复合物的靶向性对mAb225数量的变化敏感，因而在研究中保持其不变，而仅改变叶酸配体的数目。
The number of mAb225 was held constant due to the sensitivity to change in the number of this ligand, while the number of folate ligands was varied.
该配合物由结构新颖的四核铜单元和均苯三酸配体组成，其在小分子气体吸附和分子过滤等方面具有潜在的应用价值。
It contains some basket shaped building blocks, which is composed of Cu4Cl units and btc ligands, and possesses potential applicability to gas storage and molecular sieves.
漆酶的催化反应发生在铜离子形成的活性中心，但其氧化能力与氨基酸配体有密切的关系。
Main catalytic reactions of laccase occur in cu 2 + formed active center, however the level of REDOX potential is related to amino acid ligands.
漆酶的催化反应发生在铜离子形成的活性中心，但其氧化能力与氨基酸配体有密切的关系。
Main catalytic reactions of laccase occur in cu 2 + formed active center, however the level of REDOX potential is related to amino acid ligands.
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