NDM-1基因多存在于大肠杆菌（36份）和肺炎克雷伯杆菌（111份）中，携该基因的细菌对除替加环素和黏菌素外的抗生素普遍耐药。
NDM-1 was mostly found among Escherichia coli (36) and Klebsiella pneumoniae (111), which were highly resistant to all antibiotics except to tigecycline and colistin.
目的探讨生物被膜肺炎克雷伯杆菌耐药机制，为临床选用抗生素提供理论依据。
To evaluate the mechanism why bacteria growing in biofilm always resist to antimicrobial agents, and to provide the theoretical basis for selecting antimicrobial agents in clinic.
其中K1、K2型肺炎克雷伯杆菌的抗嗜中性白细胞之吞噬作用及抗细胞内杀伤作用强于非K1、K2型，因此，K1、K2型流行率较高，毒性较强。
Where K1, K2 Klebsiella pneumoniae anti-type neutrophils and phagocytosis and intracellular killing effect against stronger than non-K1, K2 type, therefore, K1, K2-based prevalence of high toxic.
目的探讨生物被膜肺炎克雷伯杆菌耐药机制，为临床选用抗生素提供理论依据。
[Objective] to evaluate the mechanism why bacteria growing in biofilm always resist to antimicrobial agents, and to provide the theoretical basis for selecting antimicrobial agents in clinic.
目的探讨生物被膜肺炎克雷伯杆菌耐药机制，为临床选用抗生素提供理论依据。
[Objective] to evaluate the mechanism why bacteria growing in biofilm always resist to antimicrobial agents, and to provide the theoretical basis for selecting antimicrobial agents in clinic.
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