使无效使不起作用或无效；
新金融产品短期获利和市场的快速增长使私营部门的监管者不堪重负或者被蒙住了双眼，使原本应该在体系中起降低风险作用的那部分机制不起作用了。
Short-term rewards in new financial products and rapidly growing markets overwhelmed or blinded private sector gatekeepers, and swamped those parts of the system that were supposed to mitigate risk.
长期以来有个问题使科学家们一直都很头疼----多数能够使小鼠变瘦的药物在人类肥胖的治疗上不起作用。
Scientists are painfully aware that drugs that can make mice thin do nothing of the sort in humans.
另一些人相信减肥药和使你出汗的特殊衣物，这些东西如果能起作用当然不错，但它们不起作用。
Others believe in slim pills and special clothes that make you sweat. It would be nice if they worked, but they don't.
以某种方式提供资料，使即些资料根本不起作用；
Third, in a certain way to provide information so that information that is more fundamental ineffective;
以某种方式提供资料，使即些资料根本不起作用；
Third, in a certain way to provide information so that information that is more fundamental ineffective;
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