目的筛选日本血吸虫童虫早期诊断抗原及其表位。
Objective To screen the early diagnostic antigens of Schistosoma japonicum and their epitopes.
目的采用顺序特异引物聚合酶链反应（PCR -SSP）建立人类白细胞抗原DR位点的DNA分型方法。
Objective To establish DNA typing for HLA-DR antigens by polymerase chain reaction with sequence-specific primers (PCR-SSP).
而T细胞表位的产生依赖于抗原加工提呈过程。
The production of t cell epitopes depends on the antigen processing and presentation pathway.
因此，抗原的加工提呈过程对T细胞表位的产生起到决定性作用。
Therefore, in the process of producting T cell epitope, the antigen processing and presentation pathway plays a key role.
目的：为了探讨噬菌体展示技术在筛选和鉴定病毒抗原表位研究中的应用前景。
Objective: to investigate the possibility of application of phage display technique in screening and identifying the virus antigenic epitopes.
确定T细胞所识别抗原分子上的短肽序列对T细胞表位进行定位，对于研究特异性免疫应答有着重要意义。
It is very crucial to identify antigen peptide recognized by t cell to study adaptive immune response and immune regulation.
在线用蛋白质二级结构预测软件分析MAGE - 4抗原表位，PCR获取MAGE - 4抗原特征表位基因。
Analyze MAGE-4 antigen epitope by online predict software of protein secondary structure and amplify the epitope gene by PCR.
本课题基于可重复使用的免疫磁珠技术，抗原表位分析预测技术，多肽合成及筛选技术，建立了一种简捷快速高效的特异抗体检测方法。
The method is based on the the immunomagnetic beads that can be used repeatedly, the technology of investigating epitopes and the technology of synthesizing multiple antigen peptides.
有关病原体、毒力因子和抗原表位的信息的编纂产生了很多有用的数据库。
The compilation of information concerning pathogens, virulence factors and antigenic epitopes has resulted in many useful databases.
目的：鉴定抑制肺癌细胞生长的功能性单克隆抗体1E2及其抗原，为治疗肺癌提供有潜力的靶向抗体治疗剂和分子靶位。
Objective: To identify a functional monoclonal antibody 1E2 against lung cancer and its antigen, so as to provide a candidate antibody drug and molecule target for the anti-lung cancer therapy.
本研究获得的单克隆抗体将为今后深入研究PRRSV病毒结构和功能，分析GP5蛋白的抗原表位，设计有效的新型疫苗等提供有益帮助。
The MAbs against PRRSV GP5 can be used for further analysis of the structure and function of PRRSV, identification of epitopes on GP5, which will be helpful for new vaccine design.
目的分析江西汉族骨髓供者人类白细胞抗原(HLA)- A、B、DRB1等位基因频率和HLA单倍型频率。
Objective To analyse the human leukocyte antigen (HLA) -a, b, DRB1 allele and haplotype frequencies in Jiangxi Chinese Han unrelated bone marrow donors.
目的从噬菌体肽库筛选日本血吸虫抗原模拟抗原表位。
Objective To screen the mimic antigen epitopes of Schistosoma japonicum from phage display peptide library.
本研究为今后选择合适的辅助分子与合成肽技术共同组建一种有效的探找超抗原T细胞表位的方法奠定了基础。
This study paved the way for choosing a reasonable assistant molecule with the synthetic peptide technique to establish a new method for localizing t cell epitopes on superantigens.
人类白细胞抗原d R位点(HLA - DR)的表达则被作为晚期(刺激后2 - 4天)T淋巴细胞活化的指标。
The expression of human leukocyte antigen-DR (HLA-DR) is taking as a maker for later phase (2-4 days after stimulate) of lymphocyte activation.
结论抗体抗原亲和力随免疫次数的增加趋向饱和，BSA的线性表位为优势表位，随免疫次数的增加比重逐渐增强。
Conclusion With the increase of the immunization times, the affinity of antibody come to mature and the proportion of dominant linear epitopes of BSA became higher.
目的建立、改进并完善从细菌表面展示随机肽库中进行抗原表位筛选及鉴定的方法。
To establish an improved procedure for isolation and identification of epitopes from a random peptide library displayed on the bacterial surface.
如果大肠杆菌中表达的VP1和VP2融合蛋白也能形成中和抗原表位，则解决了这个问题。
If the fusion protein of VP1 and VP2 that was expressed in E. coli can form neutralizing antigen epitopes, this problem is resolved.
叠加实验表明，5A5、5C12和6F5三株单抗抗原识别位点均不相同。
The results of superposable test suggest that 5A5, 5C12 and 6F5 were against different antigen epitope.
目的：分析患者血清中抗hcv抗体的抗原表位。
Objective: epitope analysis of anti-HCV antibodies isolated from patients serum.
整个筛选过程中抗原与抗体的结合在液相中完成，不仅消除了固相介质对抗原表位的影响，也更有利于噬菌体抗体与抗原的充分作用。
The binding process of antigen and antibody completed in the solution, which doesn't have the shortage of conformational changes encountered in the immobilized screening.
LPS在同一位置似乎也有共同抗原。
The LPS seemed to have a common antigen at the same position.
竞争抑制实验表明所获人源抗体片段与亲本鼠源单抗结合同一抗原表位。
Binding competition studies demonstrated that they bound the same epitope of the Ag as the parental Ab.
设计了一种新的病原体蛋白质B细胞抗原表位的筛选和重组表达方法。
A novel method was designed for disease specific B cell epitope mapping and epitope expression in e.
结论已成功构建了人hsp70与MAGE - 4抗原表位基因的原核表达载体，为疫苗研究提供了依据。
Conclusion the prokaryotic expression vector for HSP70 and MAGE-4 epitope genes was successfully constructed, which provided a basis for the development of vaccine.
在无HLAA2表型的感染者中，其感染后5年病毒抗原表位肽段既无共有序列的变异，也无琥珀突变。
However, in the HLA A2 - individual, the epitope had neither variation nor amber mutation in 5 years after infection.
对高敏受者进行抗体表位分析能够准确地预测可接受的供体抗原错配。
Analysis of public epitopes of HLA antibodies is very useful to predict acceptable mismatches.
分析它的主要功能位点表明它具有319位的糖基化位点和完整的抗原位点。
Sequence analysis result indicated GP had a glycosylation site at position 319 and whole antigenic sites.
分析它的主要功能位点表明它具有319位的糖基化位点和完整的抗原位点。
Sequence analysis result indicated GP had a glycosylation site at position 319 and whole antigenic sites.
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