行为改变、生理学上的变化或代谢解毒等抗性机制能够降低毒物到达靶标的有效剂量。
Mechanisms of resistance, such as behavioral change, physiological modification or metabolic detoxification, decrease the effective dose available at the target site.
结论：尼莫地平可能通过改变梭曼的分布，降低了血中梭曼的初始浓度而起到促进梭曼代谢解毒的作用。
CONCLUSION: Nimodipine might alter the distribution of soman and reduce the initial concentration of soman in rabbit blood, then accelerated the metabolic detoxication of soman.
药物代谢酶(DME)在药物代谢解毒和药物代谢活化中起着重要的作用，对组织器官的药物效应和毒性的易感性产生重要影响。
Drug metabolism enzymes (DME) play a significant role in drug detoxification and activation, which exert important effect on drug efficacy and sensitivity to toxicity.
维生素A：维生素A能加强免疫系统和能帮助机体解毒，特别是对矿物质的新陈代谢和内分泌功能起重要作用。
Vitamin A: Strengthens the immune system. Essential for mineral metabolism and endocrine function.
它们具有多种生物学功能，既能作为代谢酶也可作为结合蛋白在多种解毒过程中发挥作用。
They are mulifunctional proteins that act as enzymes and also as binding proteins in various detoxification processes.
促进新陈代谢，增强肝脏解毒功能。
Stimulative metabolism, enhance hepatic and alexipharmic function.
在许多害虫中发现P 450介导的解毒代谢增加导致了对杀虫药剂抗性的增加。
Increased P450mediated detoxification has been found in many insect species, resulting in enhanced insecticide resistance.
经诱导的昆虫解毒酶对不同类型杀虫剂的代谢能力并不相同，进而导致对不同药剂的敏感性变化有明显差异。
The metabolic abilities of induced detoxifying enzymes for the insecticides varied with the types of insecticides, resulting in the variations of insect susceptibility to different insecticides.
经诱导的昆虫解毒酶对不同类型杀虫剂的代谢能力并不相同，进而导致对不同药剂的敏感性变化有明显差异。
The metabolic abilities of induced detoxifying enzymes for the insecticides varied with the types of insecticides, resulting in the variations of insect susceptibility to different insecticides.
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