过去两年的一切努力将付之东流。
春节之前，我犹豫不决，害怕我取得的一切付之东流。
I was indecisive before Spring Festival. I was afraid that I might make all my previous achievements wasted.
但是他的努力可能付之东流：美国已经对开支非常敏感了。
But his push may be for naught: Americans have become allergic to spending.
移动或增加锚栓可能改变路线的原貌，让首攀者的努力付之东流。
Adding or moving bolts may alter the nature of the climb and devalue the efforts of the first ascent.
为情人柳德米拉而奔走呼告的活动却促使茂文的学术事业付之东流。
我料想这两个孩子会大哭，为他们的艰苦努力付之东流而伤心不已。
I expected the children to burst into tears, devastated by what had happened to all their hard work.
可怜的多萝西娅想到她丈夫毕生的努力可能会付之东流就悲痛难忍。
Poor Dorothea felt a pang at the thought that the Labour of her husband's life might be void.
最终，管子是会破的，停留在牙膏管里的是适者，其他的就付之东流了。
The organisms that stay in the tube of toothpaste are the fittest. The others get flushed down the drain.
一小滴水能使河堤冲垮，能使建筑倒塌，也能使人们的梦想付之东流。
A tiny drop of water washed away the land and buildings fell, floating away with other people's dreams.
这可能导致银行体系积累新的不良贷款，使近年来取得的进步付之东流。
This could result in an accumulation of new nonperforming loans in the banking system, setting back a good deal of the progress that has been achieved in recent years.
如果任何措施都没有实施，特雷蒙蒂先生在公共财政方面优秀的工作可能付之东流。
The risk if nothing happens is that Mr Tremonti’s good work on the public finances could be undone.
最糟糕的问题是用户想点击提交却误点了重置，他们填写的信息将一下子付之东流。
The worst problem about Reset is that users click the button by mistake when they wanted to click Submit. Bang - all your work is gone!
如果我们没有应对网络挑战的联邦力量，那么所有网络高手和组织的努力都会付之东流。
If we don't have a federal work force capable of meeting the cyber challenge, all of the cyber czars and organizational efforts will be for naught.
这些都是振奋人心的消息，然而一些人担心，如果股票市场稍有下跌，这些计划将付之东流。
Encouraging stuff, though some fret that any hiccup in equity markets could scupper these plans.
工业企业枯萎的落叶到处可见；农场主的产品找不到销路；千家万户多年的积蓄付之东流。
The withered leaves of industrial enterprise lie on every side, farmers find no markets for their produce, and the savings of many years and thousands of families are gone.
随着时间的推移，我对弹扬琴的感觉，就像五松先生一样付之东流，流入了哪一望无垠的大海。
Over time, I feel Yangqin shells, just five have been in vain, like Mr. Song, which entered the oasis in the sea.
为这些国家持续的提供资金至关重要，不然，2002年以来投入的九十九亿美元就会付之东流。
Sustained funding in these countries is crucial or $9.9bn invested since 2002 will have been in vain.
没有媒体的曝光，大笔金钱将付之东流。我的意思是甚至没有人注意到活动背后的品牌或者公司。
Without media exposure, hundreds of thousands of pounds would go down the drain, I mean nobody even notices the brand or the company behind the event.
在Henry实施他的计划10年后，他在岛上发现了一只白鼬，由此他认识到他的毕生的心血付之东流了。
Ten years after he began his project, Henry discovered a stoat on the island and realized his life's work had been in vain.
如果穆哈默德·布阿齐齐以及其他那些为了美好生活而献身的人的努力都付之东流，那该是多么遗憾的事儿啊。
It would be a shame if Mohamed Bouazizi and the others who have given their lives in the hope of a better life had done so in vain.
一些环境学家担忧他们曾为保护森林与过度砍伐力争了多年之后，对生物燃料的需求又将使这些努力付之东流。
Some environmentalists worry that having struggled for years to protect forests from overexploitation, demand for biofuels could undermine their efforts.
在2002年，基地内部人员给另一个同党说“太痛心了，兄弟…只有六个月，我们这些年的心血全都付之东流了。”
In 2002 an al-Qaeda insider wrote to another, saying, "Regrettably, my brother ... during just six months, we lost what we built in years."
关于小人物追求自己梦想的励志电影并不新鲜，但娱乐圈这个题材是特别的，这里可能让最多梦想之心破碎，让最大努力付之东流。
Inspirational movies about underdogs pursuing their dreams are nothing new. But the entertainment industry is special. It might be the field with the most broken hearts and most efforts gone in vain.
在最近的一篇《华尔街日报》文章中，我写到有很多待业的求职者因为在面试过程中表现得绝望或是辛酸，导致自己的受雇机会付之东流。
In a recent Wall Street Journal article, I wrote about how many unemployed job candidates blow their chances of getting hired by appearing desperate or bitter during the interview process.
一些人开始讨论回购高盛股票以提振股价的想法，而很多人担心如果高盛沦为下一个倒下的多米诺骨牌，他们的工作和资产也会付之东流。
Some discussed the idea of buying back Goldman shares in hopes of boosting its stock price, and many worried about their own employment and net worth if the company became the next domino to fall.
一些人开始讨论回购高盛股票以提振股价的想法，而很多人担心如果高盛沦为下一个倒下的多米诺骨牌，他们的工作和资产也会付之东流。
Some discussed the idea of buying back Goldman shares in hopes of boosting its stock price, and many worried about their own employment and net worth if the company became the next domino to fall.
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