目的探讨热休克蛋白90 (HSP90)在人脑恶性胶质瘤的表达及其在肿瘤增殖、分化中的作用。
Objective To probe the expression and role of the heat-shock protein 90 (HSP90) in the proliferation and differentiation of human brain gliomas.
目的探讨人脑胶质瘤中血管内皮细胞生长因子(VEGF)的表达与微血管数量(MVQ)和肿瘤良恶性程度的关系。
Objective to investigate the relationship between the expression of vascular endothelial growth factor (VEGF), the microvessel quantity (MVQ) and the grade in human brain gliomas.
目的探讨微血管密度(MVD)和基质金属蛋白酶9(MMP 9)的表达与人脑胶质瘤恶性程度及预后的关系。
Objective To explore the relation between micro vascular density (MVD), expression of matrix metalloproteinase-9 (MMP-9) and malignancy in glioma.
联合检测三者的表达水平对判断肿瘤的恶性程度有一定的参考意义,同时,这三个因子可作为判断与预测人脑胶质瘤患者预后的重要指标。
The assay of the three factors has referential significance to the estimation of tumor malignant degree, and the three factors can be used as the important markers of gliomas prognosis.
结论:成功地克隆、表达及纯化NBEAL1蛋白,NBEAL1蛋白在人脑胶质瘤组织中的表达与其恶性程度呈负相关。
Conclusion: the NBEAL1 protein has been successfully cloned, expressed and purified. NBEAL1 protein expression in glioma tissues is negatively associated with the pathological grades of glioma.
结论:成功地克隆、表达及纯化NBEAL1蛋白,NBEAL1蛋白在人脑胶质瘤组织中的表达与其恶性程度呈负相关。
Conclusion: the NBEAL1 protein has been successfully cloned, expressed and purified. NBEAL1 protein expression in glioma tissues is negatively associated with the pathological grades of glioma.
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