The vessels stained positive for antibodies to human endothelial cells, again showing that some of the cells had to come from the tumor.
这些血管对人类内皮细胞抗体呈阳性,再一次证明了一些血管细胞来自肿瘤自身。
Objective: To explore the role of vascular endothelial cells and fibroblasts derived from tumors in the tumor angiogenesis in solid tumors.
目的:探讨肿瘤血管内皮细胞和成纤维细胞在肿瘤血管形成中的作用。
Recent researches have found that TF always exists in tumor cells and neovascular endothelial cells, suggesting that TF is closely related to the growth of tumor and neovascular epithelial cells.
近年研究表明,在肿瘤组织中,TF常表达于肿瘤细胞及肿瘤新生血管内皮细胞,提示其与肿瘤生长、肿瘤新生血管的形成密切相关。
Endostatin is a kind of angiogenesis inhibitor, specific effecting in the new microvascular endothelial cells. The level of endostatin and the angiogenesis of tumor have a close correlation.
内皮抑素是一种抗血管生成的抑制因子,它特异性地作用于新生微血管的内皮细胞,其水平与肿瘤血管生成有着明显的相关性。
The effects of tumor necrosis factor (TNF) on cultured human umbilical vein endothelial cells (HUVEC) and the mechanism of circulating endothelial cell (CEC) formation had been studied.
本文以原代培养的人脐静脉内皮细胞(HUVEC)为材料,研究了肿瘤坏死因子(TNF)对HUVEC的损伤作用及循环内皮细胞(CEC)的形成机制。
More and more studies proved that the endothelial progenitor cells provide a therapeutic stratagy for the ischemic diseases and the tumor.
内皮祖细胞为缺血性疾病以及肿瘤的治疗提供了另一新的靶点。
The endothelial cells of blood vessels within the tumor were labeled by CD34 for calculating MVD.
用CD 34标记瘤组织血管内皮细胞,测定微血管密度(MVD)。
Integrin is often significantly up-regulated in activated endothelial cells during tumor angiogenesis.
在肿瘤血管生成过程中,活化血管内皮细胞整合素表达明显上调。
Conclusions the double suicide gene driven by KDR promoter has specific killing effect on KDR-expressing gastric tumor cells and venous endothelial cells in vitro.
结论KDR基因启动子可调控双自杀基因系统选择性杀伤表达KDR胃癌细胞及血管内皮细胞。
To gain a molecular understanding of tumor angiogenesis, we compared gene expression patterns of endothelial cells derived from blood vessels of normal and malignant colorectal tissues.
为了能够在分子水平上了解肿瘤的血管造影照片,我们对比了从正常和恶性结肠癌组织的血管分离到的上皮细胞的基因表达模式。
We show that endothelial cells interact closely with self-renewing brain tumor cells and secrete factors that maintain these cells in a stem cell-like state.
我们的研究表明内皮细胞与能够自我更新的脑肿瘤细胞之间存在密切的交互作用,并且能够分泌细胞因子来维持这些细胞的干细胞状态。
Increasing the number of endothelial cells or blood vessels in orthotopic brain tumor xenografts expanded the fraction of self-renewing cells and accelerated the initiation and growth of tumors.
在原位移植脑肿瘤局部增加内皮细胞或者血管的数量能够提高自我更新细胞的数量,加速肿瘤的发生和生长。
Results: Protein and mRNA of VEGF were located in endothelial cells of vascular and breast cancer cells, the expression level was elevated while the clinical staging of tumor progressed.
结果:VEGF蛋白及m RNA均定位在乳腺癌癌细胞及血管内皮细胞中,且其表达随着临床分期的增高明显增强。
Results: Protein and mRNA of VEGF were located in endothelial cells of vascular and breast cancer cells, the expression level was elevated while the clinical staging of tumor progressed.
结果:VEGF蛋白及m RNA均定位在乳腺癌癌细胞及血管内皮细胞中,且其表达随着临床分期的增高明显增强。
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