They bind to target genes and decrease their function.
它们结合到目标基因上并降低它们的作用。
Nur77 binds to specific DNA elements leading to the regulation of target genes (7).
Nur77结合到特定的DNA分子，导致靶基因的调控(7)。
DPC4 gene might become one of the target genes for pancreatic adenocarcinoma gene therapy.
DPC4有望成为胰腺癌基因治疗新的候选基因。
Ko is working to adapt a procedure used so far in pigs, cows and other animals to target genes in cloned dogs.
Ko正在研究利用目前用于猪，牛和其他动物的程序给克隆狗进行基因打靶。
Thus, it is possible to significantly suppress nonsense mutations within target genes using antisense PNAs.
由此可见，反义pna有可能在靶基因区域显著性抑制无义突变。
The relationships between TFs and their target genes can be modeled in terms of directed regulatory networks.
转录因子和它们的靶标基因之间的关系能够根据定向调节网络被模拟出来。
In contrast, comparatively few downstream target genes have been identified that are involved in organ formation.
与此相反，绝对较少的下游目的基因已被确定是在器官构成有关。
Methods RNA from human peripheral blood mononuclear cells were extracted and target genes were amplified by RT-PCR.
方法提取人外周血单个核细胞总RNA，反转录聚合酶链反应（RT-PCR）扩增目的基因；
Because of the huge plant genome, it is difficult to find out the target genes under the unclear genetic background.
植物基因组非常庞大，在遗传背景不很清楚的情况下，要从其中找出需要的目的基因实非易事。
These target genes displayed methylation - associated transcriptional silencing in breast cancer cells and primary tumours.
这些靶基因在乳腺癌细胞核原发瘤中显示了甲基化相关的转录沉默作用。
In our brains, it ACTS more like a foreman, handing out instructions to at least 84 target genes in the developing basal ganglia.
在我们的大脑中，它就像一个指挥，向基底神经节中其他至少84个基因下达指令。
This study also provided effective materials for screening more mutants of the target genes in silkworm by TILLING technology.
同时，本研究为应用TILLING技术鉴定家蚕更多目的基因突变体提供了有效的材料。
Nuclear receptors (NRs) are ligand-activated transcription factors that regulate the activation of a variety of important target genes.
核受体是配体活化的转录因子，能调控大量的靶基因。
After activation by ligand as is the case with nuclear receptors, PPARs binds to a specific element in the promoter region of target genes.
这些核激素受体由其配体(激活物)激活后，通过偶联特异的反应元件来调控多种靶基因的表达。
Molecular marker assisted selection(MAS) can provide a rapid, accurate, and efficient tool for selecting target genes in back cross breeding.
分子标记辅助选择（MAS）因其对目标基因的快速准确选择为回交育种提供有效工具。
The main procedures were: to prepare the target genes and cells, to fill the sample into the glass capillary injector and to proceed microinjection.
该技术主要包括：目的基因和靶细胞的制备、样品的灌注以及对细胞的显微注射。
Objective: to study the effect of dioscin to breast cancer cytogene expression by cDNA microarray technique, and to explore target genes of drug action initially.
目的：通过基因芯片技术研究薯蓣皂苷对乳腺癌细胞基因表达的影响，初步探索药物作用的靶基因。
The gene overlapping(ATGA) is widespread in streptomycetes, making it difficult to perform in-frame deletion or replacement for functional analysis of target genes.
链霉菌基因组中常见连续两个基因重叠的现象（如ATGA），这为基因的同框敲除或取代研究带来很大困扰。
To understand how LXR regulates LDLR, the authors examined transcriptional target genes of LXR and identified a gene that encodes a myosin interacting protein, IDOL.
为了了解LXR如何调节低密度脂蛋白受体，作者研究了LXR靶基因的转录，并确定了一个能编码肌球蛋白互动蛋白的基因，IDOL。
As a transcription factor, STAT3 participated in the control of their target genes' expression and forms a complicated network together with other transcription factors.
作为转录因子的STAT 3参与很多基因的表达和调控，并与其他转录因子形成复杂的调控网络。
It has been reported that mutant p53 can interact with other transcription factors and be recruited to their binding sites to modulate the expression of their target genes.
据报道，突变的p 53可以与其他转录因子相互作用，并且被招募到它们的结合位点以调节它们靶基因的表达。
They have been successfully used in antisense technology, for their ability to specifically bind to messenger RNA (mRNA) targets and to inhibit translation of the target genes.
由于他们能与信使核糖核酸(mRNA)靶特异性结合，进而抑制靶基因的翻译，因而在反义技术中已被成功地应用。
The tumor suppressor p53 regulates cell cycle arrest, apoptosis and DNA repair processes by controlling various target genes that contain p53 sequence-specific DNA binding sites.
抑癌蛋白p53通过调节下游靶基因的转录，参与细胞凋亡、细胞周期抑制、DNA损伤修复等多种生物学过程。
The invention relates to a skin material which comprises biomaterial and cells that carry photosensitive genes and target genes, wherein the cells are inoculated in the biomaterial.
本发明涉及一种皮肤材料，所述皮肤材料包括生物材料和携带光敏感基因和目的基因的细胞，所述细胞接种于所述生物材料中。
The basic principle, characteristic and its application of PCR in the preparation of target genes, medicine, forensic medicine, paleontology and ecology research are introduced in this paper.
本文综述了P CR技术的基本原理、特点及在目的基因制备、医学、法医学、古生物学及生态学中的应用。
In order to develop a DNA microarray to detect Steptococcus suis species, its serotype and virulence-associated genes simultaneously, a set of probes specific for the target genes were designed.
目的建立猪链球菌基因芯片检测方法，实现对猪链球菌种、致病血清型及毒力相关基因的同步检测和鉴定。
In this paper, progresses in genetic transformation of tall fescue were reviewed in terms of recipient materials, transformation methods, target genes, influencing factors and transgene inheritance.
本文从受体材料、转化方法、目标基因、影响因素、转基因遗传等多个方面综述了迄今为止高羊茅遗传转化研究所取得的进展。
In this paper, progresses in genetic transformation of tall fescue were reviewed in terms of recipient materials, transformation methods, target genes, influencing factors and transgene inheritance.
本文从受体材料、转化方法、目标基因、影响因素、转基因遗传等多个方面综述了迄今为止高羊茅遗传转化研究所取得的进展。
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