It's only when you inherit the mutation from both parents that you get sickle-cell anemia.
只有当你同时遗传了父母双方的突变，你才会患上镰刀状细胞性贫血。
Approximately 5% of the world's population are healthy carriers of a gene for sickle-cell disease or thalassaemia.
全世界近5%的健康人口携带有镰状细胞病或地中海贫血的基因。
This condition leads to shortened red blood cell survival, and subsequent anaemia, often called sickle-cell anaemia.
这一状况导致红血球存活期缩短，继而发生贫血，通常称之为镰状细胞贫血。
Approximately 5% of the world's population carries trait genes for haemoglobin disorders, mainly, sickle-cell disease and thalassaemia.
世界人口近5%携带血红蛋白疾患的特征基因，血红蛋白疾患主要包括镰状细胞病和地中海贫血。
Or blood cells may be examined for signs of sickle-cell anemia, leukemia, or other disorders.
或检测血液细胞是否有镰状细胞性贫血，白血病或其他疾病的迹象。
This has been done successfully in mice with sickle-cell disease, but will not be possible for some years in people.
在患有镰刀形细胞症的实验鼠身上此法已获成功。但是，在未来几年，此法尚无法在人类患者身上实施。
West Africans, and people of West African descent, are susceptible to a disease called sickle-cell anaemia that is virtually unknown elsewhere.
如西非人以及他们的后代易患一种叫做镰状细胞性贫血的疾病，这种病在西非之外几乎都没人听说过。
He then corrected the sickle-cell genetic defect and prodded the iPS cells to develop into the type of marrow stem cell that manufactures a mouse's blood cells.
接着，他修正了这些iPS细胞的镰刀形贫血遗传缺陷，并刺激这些iPS细胞分化发育成为能够制造小鼠红细胞的骨髓干细胞。
This image shows two red blood cells: a normal red blood cell (colored red in the background) and a red blood cell affected by sickle-cell anemia (in the foreground).
这幅图片显示了两种红血细胞：正常红血细胞(红色背景)和患有镰形细胞贫血症的红血细胞(前景)。
More recent experiments have shown that fresh tissue derived in this manner can alleviate the symptoms of Parkinson's disease and sickle-cell anemia in mouse models.
最近的实验发现，用该方法制造的新组织可以缓解帕金森病小鼠和链状细胞性贫血小鼠症状。
The system could also diagnose sickle-cell anaemia from blood samples, while fluorescent images of a stained sputum smear were sufficient to identify the presence of tuberculosis.
用这个方法能从血液样本中查出镰刀形红细胞贫血症，染色唾液涂片的荧光图像还能诊断出是否得了肺结核。
Poor blood oxygen levels and blood vessel blockages in people with sickle-cell disease can lead to chronic acute pain syndromes, severe bacterial infections, and necrosis (tissue death).
镰状细胞病患者血液含氧量低并且发生血管堵塞，可导致出现慢性和急性疼痛综合症、重度细菌感染和坏疽(组织坏死)。
One option in future may be to create stem cells from a patient's own tissue, then return these after using gene therapy to correct the genetic mutation that causes sickle-cell disease.
未来一个选择是从患者的组织培养干细胞、经基因疗法纠正导致镰刀形细胞症的遗传变异后再移植给患者本身。
Sickle-cell anaemia is passed on through a recessive gene.
镰状细胞贫血通过隐性基因遗传给后代。
Sickle-cell anemia is a blood disease that causes the cell to form a characteristic sickle-shape.
镰形细胞贫血症是一种能使细胞发生镰形变化的血液病。
Sickle-cell anemia is one of the most prevalent hereditary disorders with prominent morbidity and mortality.
镰状细胞性贫血是最流行的遗传性疾病之一，具有很高的发病率和死亡率。
Sickle-cell disease is characterized by a modification in the shape of the red blood cell from a smooth, donut-shape into a crescent or half moon shape.
镰状细胞病的特征是红血球形状发生突变，由平滑的圆圈形状改变为新月形或半月形。
Are patients with sickle cell disease at greater risk of infection?
镰状细胞病患者是否有更高的感染机会？
In one particular inherited disease, sickle cell anaemia, the red blood cells, instead of being flat discs, are sickle shaped.
在一种特殊的遗传疾病镰形细胞贫血症中，红血球不是圆盘状而是镰刀状。
A cancer drug called hydroxyurea (Droxia, Hydrea) also is used to treat sickle cell anemia.
羟基脲是一种抗肿瘤药，也可以用来治疗镰状细胞性贫血。
Hemoglobinopathies such as thalassemias and sickle cell anemia, important genetic diseases of people, have not been seen in other animals.
人的重大遗传性血红蛋白病：例如地中海贫血和镰状细胞性贫血，没有在其它动物中发现。
It is also needed for regular transfusions for people with conditions such as thalassaemia and sickle cell disease and is used to make products such as clotting factors for people with haemophilia.
地中海贫血和镰状细胞病等病症患者还需要定期输血，并且血液被用于制造各种制品，例如供血友病患者使用的凝血因子。
Other researchers are working on gene therapy as another approach to cure sickle cell disease, but progress has been slow.
其他研究者正在钻研基因疗法，这也是镰形细胞贫血症的另一疗法，然而进展很缓慢。
This is sickle cell anemia in sickle cell crisis.
出现镰状细胞危象的镰状细胞贫血。
He was a writer who worked hard for $150 a week. He never whined or complained about money or that he was born with a painful disease called sickle cell.
他写作为生，为了每周150美元的收入辛勤工作，但他从不抱怨钱的问题，也没有因为生来就患有镰刀细胞病——一种伴随着巨大的疼痛的疾病——而自怨自艾。
He was a writer who worked hard for $150 a week. He never whined or complained about money or that he was born with a painful disease called sickle cell.
他写作为生，为了每周150美元的收入辛勤工作，但他从不抱怨钱的问题，也没有因为生来就患有镰刀细胞病——一种伴随着巨大的疼痛的疾病——而自怨自艾。
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