The potential has driven nearly every major pharmaceutical company to start an RNAi program.
潜在的应用已经驱使几乎每一个主要的制药公司开展RNAi计划。
To understand RNAi and RNA in general, researchers began isolating and studying RNA molecules just 21 to 30 bases long.
为了在总体上了解RNA干扰和RNA,研究人员开始分离并研究只有21到30个碱基长的RNA。
"I think RNAi could work for anything," Rossi says. "But even if it only works for liver cancer, it would be pretty good."
“我认为RNAi对所有的病都有效,”罗西说,“但即使它只对肝癌有效,那也已经非常棒了。”
RNAi (Ribonucleic acid interference) is a technique that attacks specific genes in malign cells, disabling functions inside and killing them.
核糖核酸干扰(RNAi)会攻击恶性组织细胞里的专门基因,让其丧失功能并且最终将其杀死。
Called RNA interference (RNAi), the technique has become a standard way to control gene activity in a variety of species, earning a Nobel Prize in 2006.
这种关闭基因的技术称为rna干扰(RNAi),目前已成为控制各物种中基因活性的一个标准方法,并在2006年获得了诺贝尔奖。
RNA interference (RNAi) is a powerful tool in the study of gene function.
RNA干扰已经成为基因功能研究的强大工具。
Objective: To explore a new method for cancer treatment by RNA interference (RNAi).
前言: 目的:本研究利用RNA干扰PPO 基因,探索癌症的治疗的新途径。
Here the study history, mechanism and applications of RNAi and gene silencing are reviewed.
就RNA干涉与基因沉默的研究历史、作用机制和应用作了综述。
Conclusion: RNAi has great potential in the treatment of gastric cancer as a new gene therapy.
结论:RNA干扰技术作为一种新的基因治疗技术在胃癌治疗方面有着巨大的应用潜力。
Accordingly, at the beginning the RNAi technique can't be applied in most of the mammalian cells.
因此最初RNA干扰技术在哺乳动物细胞中的应用受到很大的限制。
It has been reported the growth of liver cancer can be effectively controlled by specific gene silencing by RNAi.
已有研究显示,RNA干扰下调肝癌形成相关基因的表达能有效抑制肝癌细胞的生长。
RNA interference (RNAi) is now established as a powerful tool to silence gene expression in a variety of organisms.
RNA干扰技术已广泛应用于沉默基因表达的研究。
Objective: To study the effect on drug resistance by RNAi mediated ERCC1 gene silencing in ovarian cancer cell line.
目的:观察rna干扰沉默ercc1基因对卵巢癌细胞耐药的影响。
In this article we summarize the mechanisms of RNA interference and the progress on anti-HBV infection studies by RNAi.
本文对RNA干扰技术在抗hbv感染方面的研究进展进行综述。
Until recently, however, the identity of the molecular scissors that actually cut messenger RNA during RNAi has remained elusive.
然而直到现在到底是哪个分子剪刀在RNA干扰的过程中剪切信使RNA仍然不清楚。
Objective: to construct and identify a lentiviral vector harboring RNAi sequence targeting the human high mobility group A1 (HMGA1) gene.
目的:构建和鉴定人高迁移率族蛋白组a 1 (HMGA1)基因rna干扰慢病毒表达载体。
This article summarizes the history of discovery, the biochemical mechanism, the characteristics and the comprehensive application of RNAi.
文章简要介绍了RNA干涉的发现史、作用机制、特点及该项技术的用途。
In this review, we focus on the potential therapeutic use of RNAi. Also reviewed, are the challenges involved in developing RNAi for clinical use.
本文介绍了RNA干扰在疾病治疗方面的应用,并就其面临的挑战进行讨论。
Objective To study the effect of RNA interference (RNAi) on HYAL1 gene mRNA expression and the invasive potential of human breast cancer cell lines.
目的研究rna干扰对透明质酸酶基因hyal1的表达以及对人乳腺癌细胞侵袭力的影响。
This review introduces the enzymes, proteins, triggers, and regulators associated with mechanisms of RNAi, as well as the applications of RNAi in biology.
本文介绍了目前RNA干扰作用机制,与之相关的酶、蛋白、“扳机点”和调节因子,及RNA干扰在生物学方面的应用。
That ability makes RNAi a potential fix for many diseases, including cancer, that arise when abnormal cells produce excessive amounts of everyday proteins.
上述的这种能力使RNAi具有一种针对包括癌症在内的许多疾病的潜在修复能力,而这些疾病常常是由病变细胞产生过量的日常蛋白质所致。
The finding, reported in the journal Nature on Sunday, offers early proof that a new treatment approach called RNA interference or RNAi might work in people.
报道于周日《自然》杂志的这一发现提供了一种早期证据,表明被称为RNA干扰或RNAi的一种新型治疗方法将可能施用于人们。
The use of the RNA interference (RNAi) to eliminate specific gene products has greatly facilitated the understanding of gene function and the therapy of diseases.
RNA干扰作为后基因组时代的一种下调基因表达的工具已被广泛用于基因功能的研究以及疾病的治疗。
It is a new way for the study of multidrug resistance of leukemia. RNAi may be a new research tool of molecular diagnosis and molecular therapy on leukemia in the future.
该技术为白血病多药耐药的基础和临床研究开辟了新思路,也为新的分子诊断和分子治疗提供可能。
Because of being able to highly specifically and efficiently silence gene expression, RNAi has the potent application in the study of gene function and gene drug development.
由于其在基因沉默中的高度特异性和有效性,在基因功能和基因药物的研究中有很大潜力。
Although the phenomenon of RNA interference (RNAi) has been discovered in many organisms, there is no evidence to support that RNAi exists naturally in a majority of mammals.
RNA干扰现象已经在多种生物中发现,但是在多数哺乳动物中尚未发现自然存在RNA干扰的证据。
As a new reverse genetic technology, RNAi is used widely in kinds of research fields, including detection of gene function, diseases therapy, plant resistance to virus and so on.
作为一项新的反向遗传学技术,RNA干扰技术正在越来越多的应用于包括鉴定基因功能、疾病治疗、植物病毒抗性研究在内的多项研究领域。
Objective Recently, a naturally occurring gene silencing mechanism triggered by double-stranded RNA (dsRNA), RNA interference (RNAi), has been described in a number of species including Drosophila.
目的近年来,双链rna介导的基因沉默(RNA干扰)已在许多动植物中发现,并成为研究基因功能的强有力的工具。
Objective Recently, a naturally occurring gene silencing mechanism triggered by double-stranded RNA (dsRNA), RNA interference (RNAi), has been described in a number of species including Drosophila.
目的近年来,双链rna介导的基因沉默(RNA干扰)已在许多动植物中发现,并成为研究基因功能的强有力的工具。
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