Reducing weight can help reduce stress on the ER, which can lower the risk of insulin resistance and the resulting conditions.

减轻体重能够帮助降低内质网的紧张度，这就能降低胰岛素抗性的几率及其导致的状况。

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In this model, higher clinical tumor stage and ER-negative status were associated with a statistically significantly greater risk for distant relapse or death.

在此模型中，更高的临床肿瘤分级及雌激素受体阴性与远处复发或死亡存在具有显著统计学差异的相关性。

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At 3 years, ER-positive patients achieved a DRFS of 97% and a significant absolute risk reduction of 11%.

在治疗的第3年，雌激素受体阳性患者获得97%的无远处复发生存率，绝对危险度大幅下降11%。

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At 3 years, ER-positive patients achieved a DRFS of 97% and a significant absolute risk reduction of 11%.

在治疗的第3年，雌激素受体阳性患者获得97%的无远处复发生存率，绝对危险度大幅下降11%。

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