Prodrug is a new drug delivery system based on polymer compounds.
大分子前药是以大分子化合物为载体的一种新的药物传输体系。
Every proton pump inhibitor so far developed is administered in a prodrug form.
迄今为止每个质子泵抑制剂都被研究开发为一个前药的管理形式。
Preferably, the active drug is more than about 10 times as active as the prodrug.
优选地，活性药物 的活性比前体药物高约10倍以上。
Gel permeation chromatography (GPC) was used to determine the molecular weight of the prodrug.
利用凝胶渗透色谱(GPC)测定了前药的分子量。
AIM: to investigate the synthesis and colon targeted characteristics of pectin ketoprofen prodrug.
目的：合成果胶酮洛芬前药并进行体外评价。
Fospropofol disodium, a water-soluble prodrug of propofol, is a new drug used in the diagnosis and sedative therapy.
磷丙泊福钠是丙泊酚的水溶性前体药物，是一种应用于诊断及治疗阶段的镇静催眠新药。
The invention relates to a mutual prodrug and a preparation method thereof based on paclitaxel and nitrogen mustard.
本发明涉及一种基于紫杉醇-氮芥的协同前药及其制备方法。
Aim to synthesize acylated prodrug of tacrine hydrochloride (THA) to improve the infiltration ability across the blood brain barrier (BBB).
目的制备盐酸他克林(THA)的酰化前体药物以提高其透过血脑屏障(BBB)的能力。
This review addresses the progress of the oral prodrugs in recent years, mainly including classical prodrug design and targeted prodrug design.
本文综述了近年来口服前药研究的进展，主要包括经典前药设计和靶向前药设计。
The flowable composition includes a biodegradable, thermoplastic polymer, an organic liquid, and risperidone, a metabolite, or a prodrug thereof.
所述可流动组合物包含可生物降解热塑性聚合物，有机液体和利培酮、其代谢物或前药。
Prodrug is an effective way to improve the oral absorption of the drugs which belong to Biopharmaceuticals Classification System(BCS) class III and IV.
前药研究是提高生物药剂学分类系统中第III和IV类药物口服吸收的有效途径之一。
The prodrug exposed to strong acid is protonated and undergoes a conformational change to its active form which is capable of inhibiting the proton pump.
前药的接触了强酸后被质子化，并且经过结构的改变成为真正能够抑制质子泵的活化形式。
The invention discloses an anti-influenza virus prodrug which is a derivative related to 1, 3-pyrazine oxazine-2, 4 diketone with a chemical structural formula (I);
本发明公开了一种抗流感病毒前体药，是有关1，3-吡嗪并恶 嗪-2，4二酮的衍生物，其化学结构式为；
Conclusion The results show that prednisolone can be delivered to large intestine by synthesized prednisolone prodrug, which has a potential in treatment of colitis.
结论泼尼松龙前体药物具一定结肠定位性，有可能成为一种具有应用前景的结肠炎治疗药物。
Objective To determine the efficacy of adenovirus-mediated suicide gene transduction combined with prodrug 5-fluorocytosine (5FC) as a therapeutic protocol for pancreatic cancer.
目的探讨腺病毒介导自杀基因联合前药5FC对人胰腺癌的治疗作用。
Mycophenolate mofetil, the prodrug of the 2-(4morpholino) ethyl ester of mycophenolic acid, has been widely applied to the prophylaxis of acute graft rejection in solid organ transplantation.
麦考酚吗乙酯是麦考酚酸的2-乙基酯前体药物，临床广泛应用于器官移植后的抗排斥治疗。
The invention further provides the application of the liver targeting anticancer nanometer prodrug system basing on the dendritic polymer in the preparation of drugs for treating solid tumors.
本发明还提供了一种基于树形聚合物肝靶向抗癌纳米前药系统在制备治疗实体肿瘤药物中的应用。
The invention further provides the application of the liver targeting anticancer nanometer prodrug system basing on the dendritic polymer in the preparation of drugs for treating solid tumors.
本发明还提供了一种基于树形聚合物肝靶向抗癌纳米前药系统在制备治疗实体肿瘤药物中的应用。
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