Objective: P53 gene involves in cell cycle regulation.
目的:p 53基因参与细胞周期调控。
Aim: To study the expression of P53 in thymomas and its clinical values.
目的:研究p 53蛋白在胸腺瘤中的表现及临床意义。
Cancer cells died following 24 hour DADS treatment that activated the p53 gene.
24小时的DADS治疗,激活p 53基因导致癌细胞死亡。
Recently, it has been found that the P53 is associated with a drug resistance to tumors.
近来,越来越多的学者注意到p53对肿瘤细胞的耐药性也具有一定影响。
The rogue genes, known as BRCA 1, BRCA 2 and P53, can be identified through a blood test.
有三种通常被称为BRCA1,BRCA2和P53的劣势基因可以通过血检进行识别。
Conclusion Adopting fusion protein P53 (PTD-P53) to treat lung cancer would be available.
结论采用PTD -P 53治疗肺癌将会是一种有效的途径。
Objective To observe the relationship between P53 gene mutation and malignant eyelid tumor.
目的探讨P 53基因突变与眼睑恶性肿瘤发生的关系。
Conclusions The expression of VEGF, P53, and P16 was correlated with glioma malignant degree.
结论VEGF、P 53、P16在胶质瘤中的表达与其恶性程度相关。
Objective To explore the significance of P53 protein expression in different type of thymoma.
目的探讨p53的表达在不同类型胸腺瘤中的意义。
The inactivation of P53 is associated with the acute transformation phase and development of CML.
P 53基因失活与慢性粒细胞白血病的急变、病情进展密切相关。
In those mice, tumors actually shrank, while the drug only slowed tumor growth in mice with defective p53.
在那些小鼠(p53仍然有功能),肿瘤真正的缩小了,而药物在p 53缺陷小鼠升上只减慢肿瘤生长。
Objective: to study the histological features and expression of P53 protein of lung cancer in aged patients.
目的:研究老年肺癌组织学特点及其P 53蛋白的表达。
AIM: to study the expression of MDM2 and mutant-type P53 proteins in primary hepatocellular carcinoma (HCC).
目的:研究MDM2和突变型P 53蛋白表达与原发性肝细胞肝癌(HCC)发生的关系。
They found that the famous tumor suppressor gene, p53, arrested the cell cycle when DADS treatment was present.
他们发现当用DADS治疗时,有名的肿瘤抑制基因p53阻止了细胞循环 。
It is suggested that the overexpression of P53 protein may be an early event in carcinogenesis of the esophagus.
结果表明:P 53基因蛋白产物的高表达在食管癌的发生中是一个早期生物学标志。
We propose that P53 pulses result from repeated initiation by ATM which is re-activated by persistent DNA damage.
我们建议P53激活是由atm不断引发的结果。而AT M被不断活化是因为持续的DNA损伤。
Conclusion the dual immunity group dyeing, may use in studying P53 and the cell keratin in pharyngeal cancer expression.
结论双重免疫组化染色法,可用于研究p 53与细胞角蛋白在鼻咽癌中的表达。
The expression of P53 protein was associated with the degree of differentiation, but not with the tumor locus and metastasis.
P53蛋白在胆管癌中表达升高,其表达与胆管癌的分化程度有关而与肿瘤部位及有无转移无关。
The protein(P53) encoded by mutant p53 gene (mtp53) not only losses these functions, but also make cell malignant transformation.
突变型p53基因的编码蛋白不但丧失上述功能,甚至出现了促使细胞癌变的作用。
Some of the mice also had defective versions of the tumor suppressor gene p53, which is mutated in about half of human lung cancers.
一些小鼠还有肿瘤抑制基因p 53缺陷,这种缺陷突变存在与大约一半的人类肺癌。
Conclusion: the peritumoral edema on MRI in supratentorial astrocytic gliomas can reflect the positive expression rate of P53 protein.
结论:幕上星形细胞瘤瘤周水肿MRI表现反映了肿瘤组织P 53蛋白的表达程度。
Objective To study the expression of P63 and P53, the relation between the expression of P63, P53 and PCNA, P16 in pancreatic neoplasms.
目的研究P53、P 63基因在胰腺肿瘤中的表达及其意义;P 63基因表达与P 53、增殖细胞核抗原(pcna)、P 16表达的关系及其意义。
Conclusion Downregulation of CGRP on the expression of P53 protein in ischemic neurons might promote the recovery of the ischemia neurons.
结论CGRP下调缺血神经元p 53蛋白的表达,可能对缺血神经元的恢复有促进作用。
But during the wound repairing, much less expression of PCNA and P53 protein in diabetic skin tissue compared with non-diabetic skin tissue.
而在创面组织修复过程中,糖尿病创面增殖细胞核抗原,P 53蛋白表达明显少于非糖尿病创面。
The researchers write that “depletion of mutant p53 may reduce drug resistance and lead to new strategies for treating cancer in the clinic.”
科学家在论文中写到“消灭p53突变体能够降低抗药性,引出临床癌症治疗的新方法。”
According to the dependence on P53, molecular mechanisms of E2F-1 induced apoptosis are classified as both P53-dependent and P53-independent.
根据诱导细胞凋亡是否依赖于P53,E2F - 1诱导凋亡机制分为P 53依赖性和P 53非依赖性方式。
The results suggested that mutation of the P53 gene may be still as an independent prognostic factor in the gastric cancers with serosa invasion.
这些结果提示:P 53基因突变可能浆膜浸润胃癌病人预后的一个重要的非依赖性因子。
Objective to investigate the relationship between the expression of P16 and P53 in brain astrocytoma with their grading of pathological histology.
目的探讨P 16和P 53蛋白的表达与脑星形细胞瘤的病理组织学分级的关系。
Cruciferous vegetables contain compounds that preferentially destroy ineffective mutant p53 tumor suppressor proteins, but leave the good ones alone.
十字花科的蔬菜含有一类物质,能够降解由p 53突变体产生的那些效率低下的抗肿瘤蛋白,而保留高效的蛋白。
Cruciferous vegetables contain compounds that preferentially destroy ineffective mutant p53 tumor suppressor proteins, but leave the good ones alone.
十字花科的蔬菜含有一类物质,能够降解由p 53突变体产生的那些效率低下的抗肿瘤蛋白,而保留高效的蛋白。
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