• Objective: P53 gene involves in cell cycle regulation.

    目的p 53基因参与细胞周期调控

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  • Aim: To study the expression of P53 in thymomas and its clinical values.

    目的研究p 53蛋白胸腺瘤中的表现临床意义

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  • Cancer cells died following 24 hour DADS treatment that activated the p53 gene.

    24小时DADS治疗激活p 53基因导致癌细胞死亡

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  • Recently, it has been found that the P53 is associated with a drug resistance to tumors.

    近来,越来越多的学者注意到p53肿瘤细胞的耐药性具有一定影响。

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  • The rogue genes, known as BRCA 1, BRCA 2 and P53, can be identified through a blood test.

    有三种通常称为BRCA1BRCA2P53的劣势基因可以通过血检进行识别

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  • Conclusion Adopting fusion protein P53 (PTD-P53) to treat lung cancer would be available.

    结论采用PTD -P 53治疗肺癌会是一种有效的途径。

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  • Objective To observe the relationship between P53 gene mutation and malignant eyelid tumor.

    目的探讨P 53基因突变眼睑恶性肿瘤发生关系

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  • Conclusions The expression of VEGF, P53, and P16 was correlated with glioma malignant degree.

    结论VEGFP 53、P16胶质瘤中的表达与其恶性程度相关

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  • Objective To explore the significance of P53 protein expression in different type of thymoma.

    目的探讨p53表达不同类型胸腺瘤中的意义

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  • The inactivation of P53 is associated with the acute transformation phase and development of CML.

    P 53基因慢性粒细胞白血病急变、病情进展密切相关。

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  • In those mice, tumors actually shrank, while the drug only slowed tumor growth in mice with defective p53.

    那些小鼠(p53仍然有功能),肿瘤真正缩小了,药物在p 53缺陷小鼠升上减慢肿瘤生长

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  • Objective: to study the histological features and expression of P53 protein of lung cancer in aged patients.

    目的研究老年肺癌组织学特点及其P 53蛋白表达

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  • AIM: to study the expression of MDM2 and mutant-type P53 proteins in primary hepatocellular carcinoma (HCC).

    目的研究MDM2突变型P 53蛋白表达原发性肝细胞肝癌(HCC)发生的关系。

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  • They found that the famous tumor suppressor gene, p53, arrested the cell cycle when DADS treatment was present.

    他们发现用DADS治疗时,有名肿瘤抑制基因p53阻止细胞循环

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  • It is suggested that the overexpression of P53 protein may be an early event in carcinogenesis of the esophagus.

    结果表明P 53基因蛋白产物高表达食管癌的发生中一个早期生物学标志。

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  • We propose that P53 pulses result from repeated initiation by ATM which is re-activated by persistent DNA damage.

    我们建议P53激活atm不断引发的结果AT M不断活化是因为持续DNA损伤

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  • Conclusion the dual immunity group dyeing, may use in studying P53 and the cell keratin in pharyngeal cancer expression.

    结论双重免疫组化染色法用于研究p 53细胞角蛋白鼻咽癌中的表达。

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  • The expression of P53 protein was associated with the degree of differentiation, but not with the tumor locus and metastasis.

    P53蛋白在胆管癌表达升高,表达胆管癌分化程度有关肿瘤部位有无转移无关。

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  • The protein(P53) encoded by mutant p53 gene (mtp53) not only losses these functions, but also make cell malignant transformation.

    突变p53基因编码蛋白不但丧失上述功能甚至出现了促使细胞癌变的作用。

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  • Some of the mice also had defective versions of the tumor suppressor gene p53, which is mutated in about half of human lung cancers.

    一些小鼠还有肿瘤抑制基因p 53缺陷这种缺陷突变存在大约一半人类肺癌。

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  • Conclusion: the peritumoral edema on MRI in supratentorial astrocytic gliomas can reflect the positive expression rate of P53 protein.

    结论幕上星形细胞瘤瘤周水肿MRI表现反映肿瘤组织P 53蛋白表达程度

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  • Objective To study the expression of P63 and P53, the relation between the expression of P63, P53 and PCNA, P16 in pancreatic neoplasms.

    目的研究P53、P 63基因胰腺肿瘤中的表达及其意义;P 63基因表达与P 53、增殖细胞核抗原(pcna)、P 16表达关系及其意义。

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  • Conclusion Downregulation of CGRP on the expression of P53 protein in ischemic neurons might promote the recovery of the ischemia neurons.

    结论CGRP下调缺血神经元p 53蛋白表达可能缺血神经元的恢复促进作用

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  • But during the wound repairing, much less expression of PCNA and P53 protein in diabetic skin tissue compared with non-diabetic skin tissue.

    创面组织修复过程中,糖尿病创面增殖细胞核抗原P 53蛋白表达明显少于糖尿病创面。

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  • The researchers write that “depletion of mutant p53 may reduce drug resistance and lead to new strategies for treating cancer in the clinic.”

    科学家论文中写到“消灭p53突变能够降低抗药性引出临床癌症治疗方法。”

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  • According to the dependence on P53, molecular mechanisms of E2F-1 induced apoptosis are classified as both P53-dependent and P53-independent.

    根据诱导细胞凋亡是否依赖于P53,E2F - 1诱导凋亡机制分为P 53依赖性P 53非依赖性方式。

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  • The results suggested that mutation of the P53 gene may be still as an independent prognostic factor in the gastric cancers with serosa invasion.

    这些结果提示P 53基因突变可能浆膜浸润胃癌病人预后一个重要非依赖性因子

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  • Objective to investigate the relationship between the expression of P16 and P53 in brain astrocytoma with their grading of pathological histology.

    目的探讨P 16P 53蛋白表达星形细胞瘤病理组织学分级关系

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  • Cruciferous vegetables contain compounds that preferentially destroy ineffective mutant p53 tumor suppressor proteins, but leave the good ones alone.

    十字花科蔬菜含有一类物质能够降解由p 53突变体产生那些效率低下的抗肿瘤蛋白,保留高效的蛋白

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  • Cruciferous vegetables contain compounds that preferentially destroy ineffective mutant p53 tumor suppressor proteins, but leave the good ones alone.

    十字花科蔬菜含有一类物质能够降解由p 53突变体产生那些效率低下的抗肿瘤蛋白,保留高效的蛋白

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