This is a significant problem for him.
这对他是个严重的问题。
Reading remained a significant problem.
读仍然是非常突出的问题。
This is a significant problem for the economy.
这是经济中值得注意的一个问题。
There are a number of reasons for the significant problem.
这个重要问题有很多原因。
Not only lack in quantity, but also significant problem in the quality.
不仅在量上存在危机，在质上面临的问题也很严峻。
And spam, as common and pervasive as it is, is a very, very significant problem.
垃圾邮件正如其常见性和广泛性一样，往往是个非常非常大的问题。
Therefore, it is a significant problem to deal with "loyalty" in idiom translation.
因此，在习语的翻译中“信”是相当重要的。
Tobacco use is still a significant problem in this country and even bigger problem globally.
吸烟在美国仍然是个很大的问题，在全球范围内更是如此。
After a period of time, people started to recognize that one significant problem was round-tripping.
经过一段时间之后，人们开始认识到其中一个显著问题是往返旅程。
The lack of professional manager loyalty is a significant problem Chinese family firms are facing.
职业经理缺乏忠诚度是我国家族企业面临的重大难题。
The laxity of export control authorities has made a significant contribution to the problem.
出口管理当局的松懈是导致此问题的重要因素。
Notwithstanding, the problem is a significant one.
然而，这个问题仍很重要。
Even for this small problem, that's a significant difference.
即使对于这个小问题，这也是很显著的差异。
The big problem is often the significant cultural barriers.
最大的问题还要是巨大的文化障碍。
The second problem is that nobody is sure that they will ever produce significant savings.
第二个问题就是:没人肯定上述措施能确保成本的大幅缩减。
A problem which may be significant is that of leakage through the door seal.
通过门密封圈的泄漏是一个重要的问题。
He brought out the significant aspects of the problem.
他揭示了问题的重要方面。
Problem drinking during the college years is a significant public health concern.
大学期间的问题饮酒行为是一个非常重要的问题。
It is a problem of significant concern to the public.
台风是海峡两岸共同关注的重大问题。
Conclusion Primary school teachers have significant mental health problem in Macau.
结论澳门小学教师存在较严重的心理健康问题。
Therefore, it is significant to study the "rear children" problem.
因此，对农村留守儿童的研究，具有重要的现实意义。
Venereal disease continues to be a significant public health problem.
结论慢性病是本社区的主要健康问题。
Therefore, it is very significant to solve the problem of oil pollution.
因此，治理石油污染有重要意义。
The method is significant for similar problem processor.
为类似问题的解决提供了参考。
Therefore, it is significant for us to realize the problem in...
而正确认识这一问题在现时代有着重要的意义。
The fact- oriented style and problem found ability have the significant positive regression.
此外，事实导向的决策风格与决策力的各因素均不存在显著的相关关系。
The fact- oriented style and problem found ability have the significant positive regression.
此外，事实导向的决策风格与决策力的各因素均不存在显著的相关关系。
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