The rate of foreign exchange, once established, was supposedly fixed.
这个汇率一旦制定就被认为是固定不变的。
Experience has shown that bad practices, once established, are difficult to shed.
经验表明不当的实践，一旦确立，是难以摆脱的。
Once established, they are extremely difficult to close.
这种医院一旦建立起来，非常难以关闭。
Once established, they are extremely difficult to close.
这种医院一旦建立起来，非常难以关闭。
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