This problem is one of great difficulty.
这个问题是一个大难题。
Of great difficulty, reluctantly to the skin.
化了很大的劲，才勉强地把皮子吞了下去。
The graduate major he registered for is interdisciplinary and of great difficulty.
他报考的研究生专业是跨学科的，难度很大！
It is of great difficulty to manufacture uniform temperature board which looks easy.
看似非常简单的均温板制作难度还是相当大的。
Partial transformation of coal industry in this country is of great difficulty and complexity.
我国煤炭产业局部转型的难度大且复杂。
They showed great perseverance in the face of difficulty.
他们面对困难表现了坚强的毅力。
He showed great courage in face of difficulty.
面对困难他表现出了巨大的勇气。
We had great difficulty in getting at the real meaning of his words.
我们很难领会他这些话的真正含义。
Actually, speaking of the product, the design makes DVR to have the very great difficulty.
其实，就产品而言，设计制造d VR是具有很大难度的。
The disintegration of soft rock often causes great difficulty to engineering.
软岩的崩解、泥化往往给工程带来困难和损失。
The measurement of thin film stress is always a problem with great difficulty.
薄膜应力的测量一直是一个困难的问题。
Studies one kind of function with great difficulty, is how many person's painstaking care!
好不容易研究出一种功能，是多少人的心血！
Thee great difficulty in education is to get experience out of ideas.
教育之艰苦在于从意念中获得经验。
Cultural Schemata often poses great difficulty in the translation of Chinese tourist publicity materials.
在翻译中国旅游宣传资料时，材料中的文化图式经常给译者带来很大的困扰。
We have had great difficulty in tracing the origin of the custom.
我们费很大尽查寻这一习俗的起源。
The great difficulty in education is to get experience out of ideas.
教育之艰苦在于从意念中获得经验。
I've had a great deal of difficulty dealing with date columns.
我处理日期列有很多困难。
Because of the noise outside, Nancy had great difficulty in focusing on her experiment.
因为外面的噪音，Nancy很难集中注意力在实验上。
Because of the noise outside, Nancy had great difficulty in focusing on her experiment.
因为外面的噪音，Nancy很难集中注意力在实验上。
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