It is with regret that I have to send this communication.
对必须发出此通讯一事，我深感遗憾。
It is with great regret that I accept your resignation.
接受你的辞呈，我感到非常遗憾。
It is with deep regret that I submit my notice of resignation from A.I.G. Financial Products.
很抱歉，我决定辞去我在AIG金融产品部门的职位。
It is with great regret that our department has to downsize to three people.
非常遗憾的是，我们的部门要减员至三人。
It is with great regret that our department has to downsize to three people.
非常遗憾的是，我们的部门要减员至三人。
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