Despite his best efforts, however, he did not end up with quinine.
尽管他尽了最大的努力，他最终还是没有得到奎宁（一种治疗疟疾的药物）。
尽管他做了所有努力。
His wonderful dream vanished into the air despite his hard efforts to achieve his goals.
他为实现自己的目标付出了最大的努力，但最后美好的梦想还是化成了泡影。
His wonderful dream vanished into the air despite his hard efforts to achieve his goals.
他为实现自己的目标付出了最大的努力，但最后美好的梦想还是化成了泡影。
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