Others, like George Church of Harvard University, fall somewhere in the middle, synthesizing individual genetic components using oligonucleotide chips, then piecing them together.
其他一些人，比如哈佛大学的GeorgeChurch，采取比较中间的位置，运用寡核苷酸芯片来合成个体基因成分，然后把它们拼在一起。
Molecular beacon is a kind of high sensitive and selective fluorescence oligonucleotide probes that is producing fluorescence upon hybridizing with their complementary DNA or RNA targets.
分子信标是一种高灵敏度、高特异性的新型荧光核酸探针。它在与互补DNA或RNA靶序列杂交时放出荧光。
These compositions include a suppressive oligonucleotide.
这些组合物包括抑制性寡核苷酸。
The labeling of oligonucleotide probes is quite important.
寡核苷酸探针的标记非常重要。
Three pairs of oligonucleotide primer were used in triplex-PCR.
应用三对具有特异性的寡核苷酸引物，进行多重pcr扩增。
Objective: To detect SARS virus by hybridization in oligonucleotide array.
目的：利用寡核苷酸芯片检测SARS病毒。
Random DNA sequencing result was identical to the results of oligonucleotide array.
部分样品的随机测序结果与寡核苷酸阵列杂交结果一致。
Phase II trials with an antisense oligonucleotide against HSP-27 in CRPC are underway.
以HSP-27为靶点的反义寡核甘酸正处于第二期临床试验中。
Objective: To set up an oligonucleotide membrane chip technique for detecting SARS virus.
目的：建立寡核苷酸膜芯片技术检测SARS病毒。
Objective: To investigate the inhibitory effect of telomerase activity by chimeric oligonucleotide .
目的：研究嵌合寡核酸对端粒酶活性的抑制作用。
Objective: to screen the high performance, specific and nontoxic anti HBV antisense oligonucleotide fragment.
目的：筛选出高效特异而无毒的抗hbv反义寡核苷酸片段。
According to the structures, DNA chip can be divided into two variants, DNA array and oligonucleotide microchip.
依其结构，DNA芯片可分为两种形式，DNA阵列和寡核苷酸微芯片。
CONCLUSION: EAAC1 antisense oligonucleotide has the neuroprotective effect against acute cerebral ischemia injury.
结论：EAAC 1反义寡核苷酸对急性脑缺血损伤有神经保护作用。
Aim To improve the synthesis of isoguanosine monomer and to synthesize isoguanosine incorporated G-rich oligonucleotide.
目的改进异鸟苷单体的合成路线 ，合成异鸟苷掺入的富鸟嘌呤的寡核苷酸。
A pair of specific primers of gene encoding phenol hydroxylase was designed by oligonucleotide high conservative sequence.
根据苯酚羟化酶基因高度保守序列设计一对该基因的特异引物。
Using oligonucleotide arrays, s. aureus resistance and virulence genes were compared between grade 1 and grade 2-4 ulcers.
应用寡核苷酸芯片后，比较1级和2 - 4级溃疡病人中，金黄色葡萄球菌的耐药性和致病基因。
Aim To design an universal sequence-tagged oligonucleotide probes for spot quality control of oligonucleotide microarrays.
目的设计一种带有通用序列标签的寡核苷酸探针以应用于寡核苷酸芯片点样的质量控制。
Human brain derived neurotrophic factor gene was used as template for oligonucleotide based site directed mutagenesis and PCR.
应用寡核苷酸诱导的定点突变和PCR技术对人脑源性神经营养因子基因进行突变，并完成了测序鉴定。
Objective: To study the antisense oligonucleotide mediated inhibition on telomerase activity and cell proliferation of GBC-SD cell.
目的：探讨反义寡核苷酸对胆囊癌细胞端粒酶活性的影响及对胆囊癌细胞生长增殖的作用。
To study the inhibitory effect of bcl-2 antisense oligonucleotide (ASODN) combined with radiation on lung carcinoma cells NCI-H446.
研究Bcl - 2反义寡核苷酸联合照射对肺癌细胞的抑制作用。
Objective To evaluate the therapeutic effect of antisense oligonucleotide targeting Survivin in the treatment of tumor-bearing nude mice.
目的评价生存素反义寡核苷酸在荷肝癌小鼠中的治疗作用。
CONCLUSION: In the construction of capillary DNA biosensors, EB can be taken as the fluorescent marker to detect the target oligonucleotide.
结论：在毛细管dna传感器构建中，溴化乙锭可作为荧光标记物对模式寡核苷酸进行检测。
The typical solid phase syntheses and their application in the syntheses of polypeptide, oligonucleotide and oligosaccharide have been described.
综述了典型的固相合成法，及其在多肽、低聚核苷酸和寡糖合成中的应用。
The oligonucleotide probe LZF-I, which is synthesized by us, can form thehybrid molecules with the simple repetitive DNA of three species of fishes.
我们自己制备的LZF—I探针，能与鱼类基因组DNA中的简单重复序列杂交形成杂交分子。
RNA profiling using a rice (Oryza sativa cv Nipponbare) oligonucleotide microarray was used to monitor gene expression in de-embryonated rice grains.
利用水稻寡核苷酸芯片检测了去胚水稻种子的基因表达。
Results: Positive SARS samples were detected by oligonucleotide array and fluorescence signal intensity was highly related to the probe's second structure.
结果：SARS阳性样品与寡核苷酸芯片杂交后出现阳性杂交信号，具有不同二级结构的寡核苷酸探针杂交信号强度不一。
These compositions including an immunosuppressive oligonucleotide can be used for the treatment of uveitis, including anterior, posterior, and diffuse uveitis.
包括免疫抑制性寡核苷酸的这些组合物可用于治疗葡萄膜炎，包括前、后以及弥散性葡萄膜炎。
Methods: Samples of subgingival plaque were detected for Aa distribution by oligonucleotide probe from 60 sites of CP patients and 10 healthy sites of healthy people.
方法：利用合成的寡核苷酸探针对60例慢性牙周炎患者60患病位点、10例健康人的10个对照位点龈下菌斑中伴放线菌放线杆菌进行检测。
Results:The standard strains of 28 mycobacteria and 9 nonmycobacteria by oligonucleotide probe array were analyzed, which showed that the oligonucleotide probe was specific.
结果：分析28种分支杆菌标准菌株和9种非分支杆菌菌株，结果显示寡核苷酸探针是特异的。
During oligonucleotide immobilization, terminal amino modification has no obvious specificity, but it can enhance the hybridization capacity of immobilized oligonucleotides.
寡核苷酸固定过程中，末端氨基修饰没有明显的特异性，但是可以提高被固定探针的杂交容量。
应用推荐