The question caught her completely off-guard and she did not know how to reply.
这个问题令她猝不及防，不知道怎么回答。
So far we do not know how much of a problem it might be.
到目前为止，我们还不知道这个问题的严重性。
That was the question; but he did not know how to answer it.
那就是问题所在；可是他却不知道怎样回答。
Unfortunately, we do not know how to build rockets that fast!
遗憾的是我们不知道怎样制造这么快的火箭！
I will willingly go away with you, but I do not know how to get down.
我很愿意和你一起走，但是我不知道怎么下去。
The child has never been in such a fine house and does not know how to behave.
这孩子从来没有住过这么好的房子，也不知道该怎么做。
Scientists do not know how much and what kinds of noises are harmful to ocean animals.
科学家们不知道有多少噪音以及何种噪音对海洋动物有害。
If people do not know how much they are eating, it can be really hard for them to stick to a diet.
如果人们不知道自己吃了多少，他们就很难坚持节食。
When students graduate from college, many of them do not know how they want to spend their working lives.
大学毕业后，许多学生不知道如何度过他们的工作生涯。
If the voters do not know how to use a computer, how do you expect them to finish the voting process through computers?
如果选民不知道如何使用电脑，你怎能期望他们通过电脑完成投票过程？
Only 6.1 percent of users have ever appealed to supervisory departments and about half of them do not know how to cancel unwanted SMS subscriptions.
仅有6.1%的手机用户曾向监管部门提出申诉，其中约一半人不知道如何取消不想要的短信订阅服务。
He did not know how he ought to behave.
他不知道自己应该怎样表现。
The wine was sweet, and she did not know how strong it was.
酒很甜，但她不知道它有多烈。
We do not even know, for example, how many stars have planets, and we certainly do not know how likely it is that life will arise naturally, given the right conditions.
例如，我们甚至不知道有多少恒星有行星，我们当然也不知道如果有适当的条件，生命自然出现的可能性有多大。
Poor girl, she did not know how fast she was nearing trouble herself.
可怜的姑娘，她自己也不知道她很快就要遇到麻烦了。
She does not know how to get to the next block.
她不清楚怎么去下一个街区。
They had a happy life, but they did not know how happy till the pretty life in the large house was over.
他们过着幸福的生活，但直到大房子里的美好生活结束了，他们才意识到之前有多幸福。
I do not know how long they lasted.
我不知道这种声音持续了多久。
我们不知道怎样使用它。
I do not know how to answer them.
我不知道如何回答她们。
They do not know how important time is.
他们不知道时间到底有多么重要。
I do not know how version 2.0 will be priced.
我不知道版本2.0将如何定价。
But we do not know how to apply these in space.
但我们不知道如何把这些应用于太空。
I do not know how to deal with this rascal.
我不知道怎么能对付这个无赖。
I am a simple person and do not know how to lie.
我是个很简单的人，不知道怎么撒谎。
He does not know how to dispose of his time.
他不知道如何安排自己的时间。
He wants to do better, but does not know how.
他想做得更好，但不知道怎么做。
We did not know how quickly it was going to move.
我们并不知道它传播的速度有多快。
We did not know how quickly it was going to move.
我们并不知道它传播的速度有多快。
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