Elucidating the extrasynaptic NMDA receptors-mediated molecular mechanisms is useful.
阐明突触外 NMDA受体参与的分子机制是非常有用的。
And we studied pharmacological properties of different sub-types of NMDA receptors.
并对所表达的NMDA受体不同亚型的药理学特性进行了研究。
This review focuses on the intracellular modulation and its mechanisms of non-NMDA receptors.
本文着重综述非NMDA受体的细胞内调控及其机制。
However, rats which did show high Numbers of NMDA receptors exhibited memory improvement when given small amounts of alcohol.
然而，大脑中有大量门冬氨酸受体的白鼠在摄入少量酒精后，记忆力则会增强。
This blocks the activity of protein molecules called NMDA receptors, which are important in many types of learning and memory.
这个药物能阻断一种叫NMDA受体的蛋白分子的活动，这种分子在多种形式的记忆和学习过程中有重要作用。
Testing done on rats showed if they did not have enough NMDA receptors, their memory did not improve when given low alcohol doses.
白鼠试验表明，如果它们大脑中没有足够的门冬氨酸受体，即使摄入少量酒精，记忆也不会得到改善。
NR2B subunits which are highly expressed in the cortex, hippocampus and olfactory bulb, are one of the key subunits of NMDA receptors.
其中NR2B是NMDA受体的主要亚基之一，在大脑皮层、海马和嗅球表达水平很高。
In addition, some scaffolding proteins and signaling proteins are also able to bind to non-NMDA receptors to influence their functions.
另外，胞内的一些骨架蛋白和信号蛋白也可与非nmda受体结合而影响其功能。
Under normal conditions, the activity of the NMDA receptors is tightly regulated to prevent nerve cells from becoming overloaded with calcium.
正常情况下，NMDA受体活性较低从而保证神经细胞不会出现钙超载。
During this period, synaptic transmission was primarily mediated by activation of NMDA receptors, suggesting that most synapses were functionally silent.
在这段时间内，突触传导以激化的NMDA受体，并显现大多数是无讯号突触。
Elucidating the extrasynaptic NMDA receptors-mediated molecular mechanisms in epileptogenesis will provide a potential cue for the effective treatment of epilepsy.
我们相信通过进一步地阐明突触外NMDA受体参与癫痫发生的分子机制，可为癫痫的治疗及预防提供合适的靶标作为参考。
However, so far, there are few studies focusing on electrophysiological properties of NMDA receptors during epileptogenesis, even less is related to extrasynaptic NMDA receptor.
但在癫痫发生阶段，目前很少有关于NMDA受体电生理学性质变化的研究，更无直接测试突触外nmda受体的报告。
RESULTS Binding force of NMDA receptors of model group was significantly higher than that of sham operation group, while tetrahydroxystilbene treatment can decreased it significantly.
结果：模型组的NMDA受体结合力比假手术组明显升高，而二苯乙烯苷治疗组可以降低模型动物的NMDA受体结合力；
Objective to investigate the role of peripheral N-methyl-D-aspartate (NMDA) receptors in the long-term hyperalgesia induced by peripheral injection of formalin in rats.
目的观察外周n -甲基- D -天门冬氨酸(NMDA)受体对福尔·马林外周注射所致长时程痛敏的作用。
Objective to investigate the role of peripheral N-methyl-D-aspartate (NMDA) receptors in the long-term hyperalgesia induced by peripheral injection of formalin in rats.
目的观察外周n -甲基- D -天门冬氨酸(NMDA)受体对福尔·马林外周注射所致长时程痛敏的作用。
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