Loss of neurofibromin expression in NF1-associated tumors is associated with elevated RAS activity and increased cell proliferation.
在与NF1相关的肿瘤中神经纤维蛋白表达的丧失与RAS活性升高和细胞增殖增加有关。
It was valuable for presymptomatic and antenatal diagnosis of NF1.
本研究方法对NF 1症状前诊断和产前诊断有重要应用价值。
The full spectrum of tumors in NF1 is beyond the scope of the text.
NF 1发生的肿瘤远超过文本所述范围。
Objective to detect the mutation on exons 32, 33 of Chinese the neurofibromatosis type 1 (NF1) gene.
目的检测中国人神经纤维瘤病1型(nf1)基因32、33外显子突变。
Benign neurofibromas are by far the most common tumor involving the gastrointestinal (GI) tract in NF1 patients.
NF 1患者胃肠道最常见的肿瘤是良性神经纤维瘤。
The genetic mutation of the NF1 leads to abnormal tumor suppression, leading to a variety of benign and malignant tumors.
NF 1基因突变导致肿瘤抑制异常，可发生各种各样的良性和恶性肿瘤。
Conclusion: the intellectual disability of NF1 is different in degree, and is affected by the degree of education and the course of disease.
结论：NF 1存在不同程度的智商及智力结构的损害并受病程及受教育程度影响。
The S100 immunohistochemical and cell shape counting results showed schwann cells were the major cells of neurofibromas in both NF1 group and non-NF1 group.
S100多克隆抗体标记及细胞形态计数显示两组瘤组织主要由雪旺细胞而不是成纤维细胞组成。
Loss of neurofibromin expression in NF1-associated tumors or NF1-deficient mouse cells is associated with elevated RAS activity and increased cell proliferation.
NF1相关的肿瘤或NF1 缺陷小鼠细胞中神经纤维蛋白的不表达与RAS的活性增加和细胞增殖的增多有关。
Approximately 10% to 25% of patients with NF1 have abdominal tumors. The primary categories of abdominal tumors are neurogenic, neuroendocrine, mesenchymal, embryonal, and miscellaneous.
大约10% - 25%的NF 1患者有腹部肿瘤，最常见的是神经源性的、神经内分泌的、间叶源性的、胚胎性的及其它。
Objective To investigate the growth characteristic, clinical manifestations, diagnosis and treatment of neurofibromatosis type 1 (NF1) in oral and maxillofacial regions for the better curative effect.
目的探讨Ⅰ型神经纤维瘤病的临床表现、诊断、治疗，为临床积累经验，提高治疗效果。
Objective To investigate the growth characteristic, clinical manifestations, diagnosis and treatment of neurofibromatosis type 1 (NF1) in oral and maxillofacial regions for the better curative effect.
目的探讨Ⅰ型神经纤维瘤病的临床表现、诊断、治疗，为临床积累经验，提高治疗效果。
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