This suggested that garlic has inhibitory and reverse effect on MNNG-induced experimental gastric carcinoma and precancerous lesion.
提示大蒜对MNNG诱发实验性胃癌具有抑制与逆转作用。
Objective: To understand the up retulatory mechanism of human REV3 gene induced by the chemical carcinogen N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
目的：了解人REV3基因对化学致癌物N-甲基- N’-硝基- N-亚硝基胍（MNNG）诱发转录上调的机制。
The preliminary study showed that Malignant transformation of NIH3T3 cells have been induced by MNNG and the cell could be used to evaluate potential carcinogenicity of chemicals.
因此，初步认为NIH3T3细胞有可能作为评定化学物质转化作用的细胞株。
Methods A rat model of chronic atrophic gastritis was made with MNNG. The rats were randomly divided into model, regulating liver and stomach, and reinforcing spleen and stomach groups.
方法运用MNNG造模致大鼠慢性萎缩性胃炎，随机分成模型组、调肝和胃组、健脾和胃组和空白组。
Conclusion: Selenium and CGRP positive cells might be involved in the prevention and inhibition of the formation of aneuploid cells in the glandular stomach mucosa induced by MNNG gavage.
结论：硒和CGRP阳性细胞可能参与了预防和抑制MNNG所致胃粘膜细胞异倍体的形成。
AIM: to find out common transcription factor binding sites in the promoter regions of the encoding genes of the co-expressive proteins induced by N-methyl-N '-nitro-n - nitrosoguanidine (MNNG).
目的：分析甲基硝基亚硝基胍(MNNG)诱导的共表达蛋白的编码基因启动子区的转录因子结合部位。
Employing the suspension cultural method, tannic acid and related compounds at non inhibitory and inhibitory concentrations against 2 NF, 4 NQO, MNNG had shown no significant antimutagenic effect.
应用悬浮培养方法，鞣酸和相关化合物在无抑制浓度和抑制浓度对2NF、4NQO和MNNG无抗突变作用。
Employing the suspension cultural method, tannic acid and related compounds at non inhibitory and inhibitory concentrations against 2 NF, 4 NQO, MNNG had shown no significant antimutagenic effect.
应用悬浮培养方法，鞣酸和相关化合物在无抑制浓度和抑制浓度对2NF、4NQO和MNNG无抗突变作用。
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