MDM2 increased drug resistance of leukemia cells to ADM.
MDM2增加了白血病细胞对阿霉素的抗药性。
The phosphorylation level of MDM2 protein was also examined by immunoprecipitation (IP).
运用免疫沉淀技术检测MDM2蛋白的磷酸化水平；
AIM: to study the expression of MDM2 and mutant-type P53 proteins in primary hepatocellular carcinoma (HCC).
目的：研究MDM2和突变型P 53蛋白表达与原发性肝细胞肝癌(HCC)发生的关系。
The results indicate that MDM2 gene may play an important role in the pathogenesis and the process of metastasis of NPC.
提示MDM2基因在NPC中的主要活化方式是高表达而不是扩增，MDM2基因的高表达可能在NPC的发生和转移过程中起着重要作用。
The effect of MDM2 on the transcriptional activity of er was detected by the reporter gene containing estrogen responsive elements luciferase (ERE-LUC).
以含雌激素反应元件的荧光素酶(ERE -LUC)为报告基因，通过检测荧光素酶活性来确定MDM2是否对ER有转录调节因子的作用。
It's suggested that the changes of p53 and MDM2, genes and proteins, may be related to the cancer transformation and poor healing of radiation-induced skin ulcers.
MDM2基因的变化及蛋白的高表达可能与放射性皮肤溃疡癌变及不愈合有关。
Objective: To investigate the expression of protein P63 and MDM2 in hypopharyngeal carcinoma and study its relation with hyperplasia and differentiation of carcinoma.
目的：探讨下咽癌中蛋白质P 6 3和MDM2的表达及其与癌增殖和分化的关系。
Objective: to detect the expression of P16 and MDM2 in gastric tumors (including both benign and malignant ones), and explore their relationship in the cell apoptosis of gastric carcinoma.
目的：检测胃肿瘤及正常胃组织中P 16与MDM2的表达，探讨其在肿瘤凋亡中的相互关系。
All 5 cases exhibited at least focal classic histologic findings. All harbored DDIT3 gene rearrangements, and none harbored MDM2 amplifications according to fluorescence in situ hybridization.
这5例至少局灶存在经典的组织学形态，荧光原位杂交检测DDIT3基因均出现重排，无mdm2扩增。
All 5 cases exhibited at least focal classic histologic findings. All harbored DDIT3 gene rearrangements, and none harbored MDM2 amplifications according to fluorescence in situ hybridization.
这5例至少局灶存在经典的组织学形态，荧光原位杂交检测DDIT3基因均出现重排，无mdm2扩增。
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