Doesn't respond as well to killed vaccines, and that's why the Salk vaccine has to be injected at a high dose.
但却对灭活的疫苗没有那样强烈反应,这也是索尔克氏疫苗为何,必须大剂量注射的原因
Now, what happened with the Salk vaccine is that Formaldehyde was used.
索尔克氏疫苗,使用了甲醛进行灭活
The strategy that Salk used was to kill the virus instead.
索尔克的方法是使用灭活病毒
Hopefully their immune systems will respond to it like the real virus but it won't be capable of replication because we've chemically cross linked it so it can't go through its life cycle.
人体的免疫系统,就会对该病毒产生免疫应答,但灭活的病毒不能复制,因为我们已经对它做了化学处理,使它无法进入生命周期
They grew the virus in monkey cell cultures, they purified the virus because you got to get all the other stuff from the cells that you're growing it in a way, they inactivated it by treating it with formalin which is just a formula-- it's just a mixture of Formaldehyde; Formaldehyde cross links proteins.
研究人员将病毒种植在猴细胞内,进行培养,并提纯病毒,在某种程度上,通过这种方法,可以得到所有类型的病毒,研究人员用福尔马林,处理病毒,使其灭活,福尔马林就是甲醛的水溶液,甲醛可以使蛋白质发生交联反应
The Salk Vaccine is also called the Killed Polio Vaccine, and some people call it KPV, also sometimes called Inactivated Polio Vaccine, IPV, but this is the vaccine I just talked about produced by Salk.
索尔克氏疫苗也叫灭活脊髓灰质炎疫苗,有人将其简称为KPV 有时也被称作,失活脊髓灰质炎疫苗,简称IPV,这个疫苗由索尔克研发,刚才讲过他
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