Why has it been so hard and why does it continue to be difficult to identify these pluripotent cells within tissues?

为什么会那么难呢,为什么在组织中识别多能干细胞,始终困难重重呢

耶鲁公开课 - 生物医学工程探索课程节选

If we understood them well enough we could potentially make any particular kind of cell in the body from those pluripotent cells.

如果我们能研究得足够透彻,我们就有可能利用这些多能干细胞,制造我们体内任何特定的细胞

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Those are called embryonic stem cells, they are self-renewing, and they are pluripotent, meaning they have many potencies.

这些称为胚胎干细胞,它们可以自我更新,且是多能干细胞,即它们有多种潜能

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Pluripotent stem cells that are capable of self-renewal to generate themselves and are capable of dividing into both bioloid and lymphoid progenitor cells.

多能干细胞,是能够通过自我更新进行自我生成的细胞,也能分化成髓系祖细胞,或者淋巴祖细胞

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This pluripotent stem cell is able to self-renew and it's able - generating committed progenitors of either the myeloid or the lymphoid lineage.

这种多能干细胞能自我更新,也可以生成定向祖细胞,可以是髓系祖细胞或者淋巴祖细胞

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So they've lost some capabilities but not many, and these are called multipotent stem cells.

它们失去了一些潜能,但不是很多,所以这些还是称为多能干细胞

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Of a million cells in the bone marrow there might only be one of these.

一百万个骨髓细胞中,也许只有一个多能干细胞

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This pluripotent stem cell from bone marrow is an example of a stem cell, an adult stem cell, a stem cell that could be identified from the blood.

这种骨髓中的多能干细胞,是干细胞的一个代表,一个成人的干细胞,可以在血液中检测到的

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As we've found cells from adult organisms that seem to be multipotential and studied them more carefully, some of their potentials turn out to be lost, they're not exactly the same.

因为我们在成人机体中找到,这些看上去是多能干细胞的细胞后,仔细研究后发现它们的一些潜能已经丢失,和胚胎中的那些并不一样

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Now, in the process of doing that they found some very rare stem cells that are called pluripotent, pluri just means many potencies.

如今在这种研究进行的过程中,他们发现了一些非常稀少的干细胞,称为多能干细胞,pluri这个前缀就是指很多能力

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