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You are asking your friend to show some sympathy for your situation.
VOA: special.2010.07.18
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When you‘re discussing your situation with a friend, you could tell them that you were doing this by using the "I'm ~ing" pattern.
当你跟一个朋友谈起你的情况时，你可以用“I'm ~ing”句型告诉他们你在做什么。
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So, you can imagine what happens as it gets deposited into your bones, which is not the ideal situation after a long day in the lab.
所以你可以想象,当它碰到你的骨头时候会如何，当你在实验室,呆了一整天后这样可不太好。
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Be open and honest about your situation.
VOA: special.2010.07.18
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Is it part of your nature to be good or bad or is it largely due to the situation that you fall in?
人性究竟是善还是恶,或者说是否应当更多地归因于所处的环境
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"It's a begging situation where you have to beg them to take your fish."
VOA: standard.2010.07.19
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Monday evening will be the time at which the midterm exam will be posted on the website, and that'll be at 6:00 pm Monday evening. You'll have a 24-hour period of time in which to find--I forget what I said--30 or 40 minutes? It'll be clear on the instructions. To just sit and treat it as if you're in an in-class exam situation, and write your essay.
周一晚上期中考试的内容会,粘贴到网站上，应该是晚上六点,你可以在一天之内抽出30到40分钟完成考试0,这在说明上都写明了,就把它当作课堂考试对待，写一篇短论文。
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But I know that your states are still in a very tough situation and too many Americans still have not felt the recovery in their own lives."
VOA: standard.2010.02.22
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It's a very easy, very direct, not at all impolite way to express your desires in any situation.
这是个非常简单而直接的句型，用这样的句型在各种情形下表达你的愿望也不会显得不礼貌。
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"Figure out your own health situation with your doctor,your family history.
VOA: standard.2009.12.25
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Your friend walks in the door and although you were nice and cozy, you can tell that outside, the situation must be different.
你的朋友走进门，尽管你觉得温暖舒适，但你明白外面肯定是冰天雪地。
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The first example is of a situation where you're not getting along with your best friend.
第一个例子是你跟你最好的朋友最近闹矛盾。
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Use it to express your statement or understanding of a situation or of a person.
你可以用它来表达你对一种情况或者是一个人的评价与理解。
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Could you tell us about your opinions on the economic situation in the U.S.?
你能跟我们谈谈你对美国经济状况的看法吗？
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Depending on the situation, on the context and on your intonation,
根据使用的语境、上下文以及你的语调的不同，
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if you do that under the situation where you've put your plasmid into these micro-organisms then you're going to have little colonies that grow many copies of the bacterial cells.
如果你在质粒已经进入了微生物,的情况下培养它们,你就会得到许多小菌落,里面长有很多增殖出来的细菌
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Now, one of the reasons why people would-- it's unthinkable for someone like me or for probably most of you to imagine giving up your rights to a kind of absolute rule, though we seem to be in a situation like that, where that's happened quite a lot recently, even in this own country.
我或者你们中绝大多数的人,很难想象会有这么多人,宁愿放弃自己的权利,而屈从于一种绝对王权的原因,尽管在我们国家,最近类似的事情层出不穷,让我们仿佛能够感同身受
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In trying to comfort your friend you could ask about his situation by using a "When" question.
为了安慰你的朋友，你可以用“When”问句来询问他的情况。
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