• It might be getting a signal from this receptor and a signal from this receptor, and a signal from this receptor.

    细胞可能同时从这个受体,这个受体,以及这个受体接收信号

    耶鲁公开课 - 生物医学工程探索课程节选

  • An example of a drug that works like that is the anti-cancer drug Tamoxifen which binds to estrogen receptors and blocks estrogen signaling.

    这种药物的一个例子就是他莫昔芬,这是一种抗癌药,能够与雌激素受体结合,阻断雌激素信号通路

    耶鲁公开课 - 生物医学工程探索课程节选

  • In the case of a ligand-receptor, a chemical signal in the form of a concentration of ligand gets converted into a biochemical signal.

    在配体-受体系统中,配体浓度这种化学信号,转化为生化信号

    耶鲁公开课 - 生物医学工程探索课程节选

  • Another characteristic of the synapse is that the post-synaptic membrane, the membrane of the cell which is going to receive the signal has receptors on it.

    突触的另一个特征是,它们都有一个突触后膜,这个膜上含有受体,可以接受信号

    耶鲁公开课 - 生物医学工程探索课程节选

  • Sometimes second messengers collect signals from a variety of different receptor systems, translate them into one kind of internal change, and the cell then just has to know about that one thing changing.

    第二信使分子能够收集,来自不同受体系统的信号,将它们转化为同一种细胞内在的变化,这样细胞就只需对一种变化作出反应

    耶鲁公开课 - 生物医学工程探索课程节选

  • Now, in this cartoon here I've shown a variety of different receptors just to show just to remind you of the different families of receptor molecules that could be involved in receiving and translating a signal.

    这个动画中,我向你们展示了各式各样的受体,为了让你们记住不同族的受体分子,它们都涉及信号的接受和翻译过程

    耶鲁公开课 - 生物医学工程探索课程节选

  • The cell that's producing the signal produces enough of the molecule so that it enters the bloodstream, it circulates throughout your body, eventually it reaches a cell at a great distance, which has a receptor for that ligand and the signal gets received.

    发出信号的细胞产生信号分子,数量十分充足 能够进入到血液中,信号随着血液流遍全身,最终到达较远处的细胞,在这些细胞上有与配体配对的受体,信号被细胞接收

    耶鲁公开课 - 生物医学工程探索课程节选

  • It gets produced in response to a signal so there's a binding of a ligand to a receptor, the enzyme that does this conversion is activated and more cycle AMP is released.

    这类分子的产生是对信号做出的一种反应,当配体和受体结合时,催化这种转化过程的酶被激活,更多的cAMP释放出来

    耶鲁公开课 - 生物医学工程探索课程节选

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