• There's a lot of words here, long words, pre-synaptic, post-synpatic, but pre, post, you get the idea. Caitlin?

    我讲了一大堆生词 长词,突触前,突触后,但是前和后的意思你们明白吧,凯特琳

    耶鲁公开课 - 生物医学工程探索课程节选

  • When these vesicles dump their contents into the synaptic cleft, the concentration of these ligands rise.

    当这些小泡将其内含物释放入突触间隙,这些配体的浓度即增加

    耶鲁公开课 - 生物医学工程探索课程节选

  • At the same time though, connections between neurons grow like crazy and they-- and this process of synaptic growth where there are the connections across different synapses peaks at about two years.

    但与此同时,神经元之间的联结也在疯狂的生长,这个在不同突触间,形成联结的突触发育过程,在两岁时达到顶峰

    耶鲁公开课 - 心理学导论课程节选

  • Those receptors, some fraction of them, are specific for the ligand that the pre-synaptic cell releases.

    这些受体 其中一部分,特异性地结合突触前细胞释放的配体

    耶鲁公开课 - 生物医学工程探索课程节选

  • Another characteristic of the synapse is that the post-synaptic membrane, the membrane of the cell which is going to receive the signal has receptors on it.

    突触的另一个特征是,它们都有一个突触后膜,这个膜上含有受体,可以接受信号

    耶鲁公开课 - 生物医学工程探索课程节选

  • When an action potential comes down this pre-synaptic axon, when it reaches this point here, it sets off the process of these vesicles dumping their content into the synaptic cleft.

    当动作电位到达轴突的突触前膜时,当到达这一点时 小泡就将其内含物,排放到突触间隙中去

    耶鲁公开课 - 生物医学工程探索课程节选

  • It's called the synaptic cleft and it's filled with extracellular fluid.

    这一空间叫做突触间隙,中间充满了细胞外液

    耶鲁公开课 - 生物医学工程探索课程节选

  • another thing that you'd find if you looked inside the axon terminals of any of these pre-synaptic membranes, you'd find lots of vesicles or some membrane bound compartments that contain special chemicals called neurotransmitters.

    如果你仔细观察,突触前膜的轴突末梢内部,你会发现很多小泡,即膜包被的结构,包含有称为神经递质的特殊化合物

    耶鲁公开课 - 生物医学工程探索课程节选

  • In some cells they're recycled, that is the cell is able to take up the neurotransmitter after it's released and restore it, but most often there are enzyme systems inside the pre-synaptic membrane where those neurotransmitters are synthesized.

    在一些细胞中神经递质可以循环利用,这些细胞可以吸收,已经释放出的神经递质并重新储存起来,但更常见的是突触前膜中含有酶系统,在此合成神经递质

    耶鲁公开课 - 生物医学工程探索课程节选

  • Because this post-synaptic neuron is going to be receiving different signals from different cells, it's decision about what to do next, and the what to do next is either create an actual potential or not create an action potential.

    因此突触后神经元可以接收,来自不同细胞的不同信号,然后决定后续反应,后续反应包括产生动作电位,或者不产生动作电位

    耶鲁公开课 - 生物医学工程探索课程节选

  • Well, one reason to do this is because on each post-synaptic neuron there might be many axons coming together at once, and each one might be generating a different kind of signal, through maybe even different neurotransmitters.

    嗯 一个原因是在每个,突触后神经元上可能有,许多同时到达的轴突,每个都可能通过不同的神经递质,产生不同的信号

    耶鲁公开课 - 生物医学工程探索课程节选

  • If you could look inside a pre-synaptic axon terminal, you would find one of the characteristics is that it's loaded with these vesicles and they're just sitting there waiting to receive an action potential so that they can immediately dump their contents.

    如果你能够一窥突触前的轴突末梢内部,你将会发现一个共同特征,神经递质都装载在小泡中,时刻准备着等待动作电位激活,以便迅速释放其内含物

    耶鲁公开课 - 生物医学工程探索课程节选

  • One is that there's a physical space in between the two cells, so the axon of what's called the pre-synaptic neuron, or the neuron that's bringing a signal into the synapse, the axon terminal is physically separated from the dendrite of the next cell.

    一是两个细胞间有一定的物理空间,所谓的突触前神经元,也就是将信号传递到突触的神经元的,轴突的末梢,同下一个细胞的树突间被物理性分离开

    耶鲁公开课 - 生物医学工程探索课程节选

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