One of the things that happens is that certain cells within your body process the vaccine or the antigen and we talked about that.

在人体内,发生的反应之一是,特定的细胞对疫苗或者抗原做出反应,之前我们讨论过这个

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So, every time you're exposed to a new vaccine or a new antigen you go through this primary response before you have the secondary response.

所以,每当你接触到新疫苗或是新抗原,在再次免疫之前,机体将会经历这样的初次免疫过程

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Again, these are antibodies that are specific to that antigen or vaccine that we introduced.

我再说一次,这些抗体针对于,我们所接种的抗原或疫苗特异产生

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From a technological perspective, antibodies are incredible tools because antibodies are molecules that are specifically designed to bind to a particular antigen or a particular chemical.

从技术角度上来说,抗体是一种令人难以置信的分子,它们被设计来,特异性地结合抗原,或者某种化学物质

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Usually the cellular means that they get rid of is that instead of an antibody being produced, you activate a population of cells that will specifically go and hunt down the foreign antigen, or more commonly, cells that contain the foreign antigen.

通常细胞免疫意味着,不用生成抗体就能清除抗原,你激活了一个细胞类群,这一类群能够,并杀伤外源抗原,或者更常见的是,杀伤含有外源抗原的细胞

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But this antigen presenting cell is more likely a professional antigen presenting cell, or a subset of cells of your immune system that are specialized in ingesting foreign particles and displaying their contents to the rest of the immune system.

但这种抗原呈递细胞更加类似于,专职抗原呈递细胞,或者是体内免疫细胞中的一个亚群,专门从事吞噬异己物质,并告知免疫系统的其他细胞的工作

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You could probably find some antigens that don't follow exactly this behavior, but in general, this is the kind of behavior you would see on first exposure to an antigen or vaccine, called the primary exposure, and on subsequent exposure to an antigen or vaccine called the boost.

可能你也会发现,一些抗原并不完全遵循这种模式,但通常来说,在你首次接触一种抗原或疫苗时,都能观察到这种模式,它被称为初次免疫,而接下来的,再次接触抗原或是疫苗被称为增强免疫

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One of the things that I didn't mention before is that when you get this primary response and then the secondary response, if you looked at the antibodies that are generated during the primary response, again we're only looking at antibodies that bind to the particular antigen or vaccine that we have used for the priming.

还有一点我之前没有提及,当你获得初次免疫,以及再次免疫之后,如果你仔细观察抗体,观察那些在初次免疫中生成的抗体,这次我们同样只是观察抗体,那些与我们在初次免疫中所用到的,特定抗原或疫苗相结合的抗体

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The other thing that I want to do today is try to tie this discussion on vaccines a little bit more closely with what we talked about last week, in terms of what happens inside your body when you receive a vaccine or when you're exposed to an antigen, and how the immune system actually responds to that.

还有就是,我希望可以,把今天关于疫苗的讨论,与我们上周讲过的内容,结合得更紧密一些,当接种疫苗,或者是接触抗原时,人体将会发生怎样的变化,以及免疫系统对疫苗产生何种应答

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