It's very water soluble and it's a big molecule, a very big molecule; it can't naturally get inside cells on its own.

它是一个水溶性极强的大分子,非常非常大的分子,质粒在自然状态下并不能自己进入细胞

耶鲁公开课 - 生物医学工程探索课程节选

It's a big change in some of these very poor villages to get a cow.

奶牛对这些赤贫的村庄来说可是生财之道

耶鲁公开课 - 金融市场课程节选

The chateau was so big that when it freezes, they were trying to get to the bathroom and most of them never made it and peed on these long corridors that some of you have seen.

那城堡太大了,以至于到了冬天结冰的时候,那些贵族们连想去卫生间都去不了,只能在长长的走廊里方便,如你们中有些人见过的那样

耶鲁公开课 - 欧洲文明课程节选