It's a mechanism that they have evolved in order to prevent foreign genes from entering a cell and being expressed.
它们进化出这种机制来,防止异源基因进入细胞并表达
Other cells in the immune system recognizing that this is a foreign molecule, but is being presented in the context of a 'self' cell.
免疫系统中的其他一些细胞,识别到它是非己物质,但它已经被识别为己方细胞
The notion is, if there's something foreign that's being produced inside this cell, then that cell must have been corrupted in some way and it has to be gotten rid of.
免疫反应的规矩是这样的,如果某些外源物在你细胞内产生,那说明这个细胞的某些地方,已经被损害了所以必须被清除掉
But this antigen presenting cell is more likely a professional antigen presenting cell, or a subset of cells of your immune system that are specialized in ingesting foreign particles and displaying their contents to the rest of the immune system.
但这种抗原呈递细胞更加类似于,专职抗原呈递细胞,或者是体内免疫细胞中的一个亚群,专门从事吞噬异己物质,并告知免疫系统的其他细胞的工作
Taking foreign genes, genes that aren't naturally expressed or might not even exist inside a cell and putting them there and putting them there in a way where they work, and by work meaning the gene gets expressed or translated into a protein.
将异源基因,即那些在细胞中原本不表达或者,根本不存在的基因转入细胞并让它们工作,工作就是指让基因持续表达并合成蛋白质
That's making the cell look foreign because some of that foreign protein is on the surface with MHC1.
这使得整个细胞亦被视为外源物,因为某些外源蛋白,和MHC1共同出现在细胞表面
Because it has MHC-1, your MHC-1 on it, this T-cell recognizes that it's one of your cells but it has a foreign antigen associated with it.
因为该细胞上有MHC-1,T细胞将这些细胞识别为自身细胞,但这些细胞带有异己抗原
Immune cells recognize it, and they recognize it by a very special form of receptor-ligand interaction where the ligand is MHC1 with the foreign antigen and the receptor is a receptor called the T-cell receptor complex.
免疫细胞识别出染病细胞,通过一种特殊形式的,受体配体协作机制识别出来,其中的配体是同,外源抗原共同出现的MHC1,而这其中受体是T细胞受体复合体
So, when the right signal is received, the right T-cell finds your host cell with a foreign virus in it, the first thing that happens is that this T-cell becomes activated and it starts reproducing, making more copies of itself.
所以 当接收到正确的信号,恰当的T细胞寻觅到,感染外源病毒的细胞时,首先发生的是,T细胞被激活并开始增殖,制造更多自身拷贝
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