• Here the unique thing was that there's a restriction site inside that is present in normal DNA and not present in sickle DNA.

    刚才例子中,特性就是在正常的基因中,有酶切位点,而在患者的基因中却没有

    耶鲁公开课 - 生物医学工程探索课程节选

  • DNA also has this sort of combinatorial system where you have a finite number of, I guess, bases or amino acids that could combine to a possible infinity of strings of DNA strings.

    脱氧核糖核酸也拥有这种组合系统,你的生物基础或氨基酸数量是有限的,但却能组合出,几乎无限的脱氧核糖核酸螺旋结构

    耶鲁公开课 - 心理学导论课程节选

  • Then we're going to take these plasmid vectors and we're going to somehow put them in contact with cells in such a way that the cells ingest the DNA and they use it.

    然后要使这些质粒载体,以一种特别的方式与细胞接触,让细胞吞入质粒载体并使之表达

    耶鲁公开课 - 生物医学工程探索课程节选

  • That's common sense. This is part of your DNA, And then their final product is an object, a b which ends up at a temperature or a warmness which is in between the hot and the cold.

    这是常识,是你的一部分,它们的最终产物是一个物体,其温度或温暖程度,介于热与,冷之间。

    麻省理工公开课 - 热力学与动力学课程节选

  • This might be a polio virus, for example. The example I've given here is a virus that contains DNA as its genetic material.

    例如 这个应该是,小儿麻痹症病毒,我曾在这里展示过,一种将DNA作为遗传物质的病毒

    耶鲁公开课 - 生物医学工程探索课程节选

  • That information gets put into action through a process, a biological process called transcription, where particular regions of DNA are transcribed into RNA.

    信息通过某种过程起到作用,这个生物学过程叫转录,在转录过程中,DNA的特定区域转录成RNA

    耶鲁公开课 - 生物医学工程探索课程节选

  • Now remember that only appears in DNA and appears in RNA, and so can also form a hydrogen binding pair with .

    还要记住T只出现在DNA中,而U出现在RNA中,U和A也可以通过氢键结合就可以了

    耶鲁公开课 - 生物医学工程探索课程节选

  • The first step is we had to be able to take this circular DNA and cut it to create a site for our new gene to be added.

    第一步是切割环形DNA,以创造出一个整合新基因的位点

    耶鲁公开课 - 生物医学工程探索课程节选

  • Then we'll talk about engineering of DNA and why this has been such - not only a rapidly growing and advancing area but one that's so important for Biomedical Engineering.

    然后我们会谈论DNA工程,以及为何它不仅,是一个向前飞速发展的领域,而且对生物医学工程十分的重要

    耶鲁公开课 - 生物医学工程探索课程节选

  • In order to have DNA you have to make DNA and your cells are continually making DNA inside your body, through a process of DNA synthesis and that synthesis is occurring because of the presence of an enzyme, a protein called DNA polymerase.

    为了使每个细胞都具有DNA,身体通过一个叫做DNA合成的过程,不停的生产DNA,这个合成过程是在,一种酶的催化下进行的,这种酶叫做DNA聚合酶

    耶鲁公开课 - 生物医学工程探索课程节选

  • They integrate their DNA into the host genome and you might not want to make that kind of a change in the cell.

    而且也许你也并不想让逆转录病毒基因,整合进宿主的基因组

    耶鲁公开课 - 生物医学工程探索课程节选

  • So DNA is replicated using one strand of the DNA as a template.

    所以DNA复制是以DNA单链为模板的

    耶鲁公开课 - 生物医学工程探索课程节选

  • Some of them are changes in the - not the sequence of DNA, not the sequence of nucleotides in the DNA but the chemistry of DNA around that the way that it's packed into a nucleus.

    某些改变不是发生在DNA序列上,不是在DNA的核苷酸序列上,而是发生在DNA包装进细胞核的,一系列化学变化中

    耶鲁公开课 - 生物医学工程探索课程节选

  • The goal of that was to take for a typical human, or for a typical - in the case of the human genome project maybe you're looking at fruit flies, you want to look at all the DNA in a fruit fly, but to look at the sequence of base pairs that makes up human DNA and write them all out; we'll talk about that later.

    这个计划的目的是,建立一个有代表性人类的基因顺序,或者说是典型的人类基因组,就人类基因组计划来说,或许你在研究果蝇,你想观察果蝇内的所有DNA,而人类基因组计划是观察组成人类的,DNA的碱基对顺序并且将它们记录下来,我们不久之后会讨论这些内容

    耶鲁公开课 - 生物医学工程探索课程节选

  • We talked about the structure of DNA, how it works in terms of a physical chemical model of the DNA molecules.

    上节课我们讲了DNA的结构,从理化模型的角度讲了,DNA分子是如何工作的

    耶鲁公开课 - 生物医学工程探索课程节选

  • This is a much more efficient way to get DNA for a gene that you're interested for a couple of reasons.

    用这个办法能更有效率地获取你,感兴趣的基因的DNA,原因如下

    耶鲁公开课 - 生物医学工程探索课程节选

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