• In this case, a receptor tyrosine kinase is a receptor molecule that binds a ligand at its surface outside the cell and initiates this enzyme activity - this kinase activity - and causes phosphorylation of another molecule.

    在这个例子中,酪氨酸激酶受体可以,在细胞表面区域与配体结合,从而激发出,激酶的活性,使其能够磷酸化另一类分子

    耶鲁公开课 - 生物医学工程探索课程节选

  • Insulin, the ligand binds to its receptor, creates a change through a kinase activity that's exposed, which leads to other biochemical changes, which leads to a change in cell behavior - in this case the cell behavior is that more glucose transporters are brought to the membrane and more glucose can enter the cell.

    胰岛素,一种能够与受体结合的配体,通过其暴露出的激酶活性引起的变化,导致了其它后续生化变化的发生,进而使细胞行为发生改变,这个例子中的细胞行为就是,更多的糖载体被带到细胞膜表面,这样更多的糖分子进入到细胞内部

    耶鲁公开课 - 生物医学工程探索课程节选

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