A big problem with this is a lot of Freudian theory is claimed to be validated in the course of psychoanalysis.

这里存在的一个大问题便是,精神分析理论中的很多内容,被认为是能够在精神分析的过程中,得到证实的。

耶鲁公开课 - 心理学导论课程节选

But there's a big confound, there's a big problem in studies of those kind of relationships.

但是有一个让人混淆的问题,存在于这种关系的研究中。

耶鲁公开课 - 心理学导论课程节选

Portion sizes, and we'll devote a class to this later on, have gone way up and that's a big problem, the amount of processing I mentioned.

食物份量直线上升,这是个问题,我们将专门用一堂课讲这个,即刚才提到的食品加工程度的问题

耶鲁公开课 - 关于食物的心理学、生物学和政治学课程节选

It's kind of unsettling because we like to know what things are, but at the same time it's not really a big problem because as long as we know about the fact that a certain notion of literature exists in certain communities we can begin to do very interesting work precisely with that idea.

可能会有点让人不安，因为我们总想知道事物的定义，但知不知道,实际上问题不大,只要我们知道在特定群体中对文学有特定的认识,我们就能在这种认识上做文章。

耶鲁公开课 - 文学理论导论课程节选

But,there was a big problem, that for all of his failings,human failings, and there were indeed many, and his intellectual limitations which were daunting, he was a man of faith and loyalty to his principles, for better or for worse,in this context.

但是他的弱点,人性的弱点,是个大问题,而且他的弱点确实很多,还有他的智力界限也令人沮丧,他是个固执于自己原则的人,不管原则是好是坏

耶鲁公开课 - 1871年后的法国课程节选