One can also purify parts of the protein, that is, parts of the virus, that is, "Do I really need to deliver the whole virus?"

人们还可以纯化部分蛋白质,也就是病毒的某些部分来制造疫苗,那么还需要接种完整的病毒吗

耶鲁公开课 - 生物医学工程探索课程节选

Just use a piece, an antigenic piece of the virus.

只用一部分病毒,就是其具有抗原性的部分

耶鲁公开课 - 生物医学工程探索课程节选

If the immune system recognizes only small pieces of the virus and mounts an immune response to that, how about if I just take these pieces of a virus like some structural subunit, some piece of protein and use that as a vaccine?

如果免疫系统识别出病毒的一小段,就可以诱发起免疫应答,那么如果我仅用一小部分病毒,比如一些结构性亚基 一些蛋白质的片段,来作为疫苗的话,会如何呢

耶鲁公开课 - 生物医学工程探索课程节选

We talked about host cells that are perhaps infected with a virus, displaying pieces of that virus, antigenic pieces of that virus in the context of a surface receptor called MHC-1, presenting that.

我们说到过,可能受到病毒感染的宿主细胞,表现出病毒的一部分特征,病毒的抗原部分,其表面受体称为主要组织相容性抗原-1,MHC-1负责呈递抗原

耶鲁公开课 - 生物医学工程探索课程节选