Particularly if you compare them with hair cells that are present in the mammalian and the human and mouse cochlea.
尤其是与哺乳动物如人和老鼠的,耳蜗中的毛细胞相比。
And after a toxic insult, they are gone. This is what the inner ear of a person who is deaf looks like.
受到损伤后,毛细胞没了,耳朵失聪的人的内耳就是这幅摸样。
And bathing inside the inner ear fluids where they become stimulated by sound waves and acceleration forces.
毛细胞悬浮在内耳液中,接受声波和其它外力的刺激。
On the top you see where the hair cells are located in the human cochlea.
幻灯上方显示的是,人耳蜗内毛细胞的位置。
I want to illustrate one of the reasons why it has been so difficult to get a grasp on the hair cells in the inner ear.
我想用图例为大家说明一下,为什么难以捕获内耳中的毛细胞。
And in red is a hair cell marker that labels sensory hair cells and the yellow color is the composite color of the green and the red.
红色部分是遗传标记,代表的是听觉毛细胞,黄色是,红和绿两色的复合色。
This is an example at the bottom of a native cochlea hair cell.
这只是耳蜗毛细胞发育的一个例证,结合这一技术和其它技术。
The name giving part for the hair cell is so-called a hair bundle.
所以叫毛细胞,是因为这种细胞有一个发状的纤维束。
This was a huge number for me up until 2 weeks ago Besides the 100 billion neurons in the brain . there are 12-15 thousand cochlear hair cells.
直到两周前,这对我来说还是个庞大的数字,除了这一兆亿个神经元外,还有12,000到15,000个毛细胞。
And the hair cells are the dark blurbs in there.
毛细胞就位于图中的黑色区域。
Hair cells that are inside your brain are very scarce.
毛细胞非常稀少。
There are only 12,000-15,000 in the human cochlea.
耳蜗内的毛细胞只有12000到15000个。
So the two points of interest of research are how does it work this conversion of mechanical energy into electrical energy how are we able to bring back lost hair cells to cure deafness.
因此这项研究的两个关键点,一是机械能,是如何转化成电能的,我们能不能通过修复受损的毛细胞,来治疗耳聋。
It is called the Hair cell.
叫做毛细胞。
This conversion from a mechanical energy into a chemical energy can be nicely visualized when one fills a hair cell with a sensitive die that responds to the calcium ions that influx into the cell.
如果在毛细胞中注入,对钙离子敏感的物质,可以精确地模拟,这一机械能到化学能的转化过程。
If these 8 million people , would correspond to the number of neurons in the brain, the equivalent of the hair cells that you could get out of a single cochlea would be equivalent to one person walking down 42nd street.
如果这八百万人,相当于大脑中的神经元数量的话,能从一个耳蜗内取出的毛细胞,就好比是,第42大街上的某位行人。
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