They prevent the ligand from reaching its natural receptor, and so that antagonizes or inhibits the function of the natural ligand.

它们能够阻止配体与受体的结合,这样就拮抗或者说是抑制了配体的功能

耶鲁公开课 - 生物医学工程探索课程节选

What insulin is doing inside your body is acting as a ligand for insulin receptors which stimulate certain kinds of cellular responses.

胰岛素在体内的功能就是作为,胰岛素受体的配体,刺激产生某种细胞效应

耶鲁公开课 - 生物医学工程探索课程节选

Sometimes you can design drugs that act like a natural ligand without being the natural ligand.

有时你能设计具有天然配体功能的药物,但它不一定和天然配体相同

耶鲁公开课 - 生物医学工程探索课程节选

You took biology in high school, you learned the names of these organelles and their principle functions, the nucleus, the endoplasmic reticulum, the Golgi apparatus, mitochondria, lysosomes.

你们高中学过生物,学过这些细胞器的名称,和基本功能,细胞核,内质网,高尔基体,线粒体,溶酶体

耶鲁公开课 - 生物医学工程探索课程节选