• What a kinase enzyme does is that it recognizes this protein, and for example, the tyrosine that's on the protein.

    激酶能够识别这类蛋白,例如,包含酪氨酸的蛋白

    耶鲁公开课 - 生物医学工程探索课程节选

  • They're making that because you need this protein insulin, it's a hormone, and it's important for sugar metabolism in your body.

    它们产生胰岛素蛋白是因为你需要它,胰岛素是一种激素,它在糖代谢中起着非常重要的作用

    耶鲁公开课 - 生物医学工程探索课程节选

  • The kinds of proteins that sit on a cell surface and form adhesion junctions with neighboring cells, that's one class of cells on the surface.

    这些蛋白位于细胞表面,和相邻的细胞建立粘附链接,这是细胞的一个种类

    耶鲁公开课 - 生物医学工程探索课程节选

  • It's on the gene for hemoglobin and the hemoglobin that you produce if you have sickle cell anemia is not quite right because there's one base difference.

    这个缺陷基因和血红蛋白有关,如果你有镰状红细胞贫血症,那你所产生的血红蛋白就不太正常,因为这里有一个碱基不同

    耶鲁公开课 - 生物医学工程探索课程节选

  • Often the state of a protein depends on whether it's phosphorylated or not.

    蛋白的状态通常取决于,它们是否被磷酸化

    耶鲁公开课 - 生物医学工程探索课程节选

  • Now, you all know that we can make irreversible changes in proteins, you can denature them completely, that's what happens when you cook an egg for example.

    现在你们都懂蛋白能够发生不可逆的改变,能够完全变性,比如在你煮鸡蛋的时候就是这样

    耶鲁公开课 - 生物医学工程探索课程节选

  • It's a protein that's produced by other cells in the body and when it's enriched in a certain area it stimulates more production of red blood cells.

    这种蛋白由体内的另一种细胞生成,而当其在某处富集时,就会刺激红细胞生成

    耶鲁公开课 - 生物医学工程探索课程节选

  • So, those wrong proteins get presented on MHC1 and your immune system can kill the cell because it's a tumor cell.

    所以 当这些错误的蛋白,同MHC1一起被呈递,你的免疫系统就可以消灭这些肿瘤细胞

    耶鲁公开课 - 生物医学工程探索课程节选

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