So, every time you're exposed to a new vaccine or a new antigen you go through this primary response before you have the secondary response.

所以,每当你接触到新疫苗或是新抗原,在再次免疫之前,机体将会经历这样的初次免疫过程

耶鲁公开课 - 生物医学工程探索课程节选

One of the things that I didn't mention before is that when you get this primary response and then the secondary response, if you looked at the antibodies that are generated during the primary response, again we're only looking at antibodies that bind to the particular antigen or vaccine that we have used for the priming.

还有一点我之前没有提及,当你获得初次免疫,以及再次免疫之后,如果你仔细观察抗体,观察那些在初次免疫中生成的抗体,这次我们同样只是观察抗体,那些与我们在初次免疫中所用到的,特定抗原或疫苗相结合的抗体

耶鲁公开课 - 生物医学工程探索课程节选

If we did the experiment where on this booster we included not only the initial antigen but some unrelated antigen, the response to the unrelated antigen called B here, looks like a primary response.

如果实验中我们使用的后续疫苗,不仅包括原抗原,还包括一些无关抗原,这里将对无关抗原的应答称为B,该应答就如同初次免疫一样

耶鲁公开课 - 生物医学工程探索课程节选

Right, but if you just got the primary exposure, wouldn't the secondary response automatically-- not a booster shot, just the secondary response, because you were exposed?

但这时你已经获得这样的初次免疫,而因为你已经天然感染过该病毒,那么,在没有加强针的情况下,二次免疫是否无法自动发生

耶鲁公开课 - 生物医学工程探索课程节选