"And with regard to the burden of disease it more than doubled,it increased over that 16 year period of time about 127 percent."

VOA: standard.2010.08.10

Many of us would find that was, as I say, a burden-- something hanging constantly over us interfering with our ability to enjoy life.

我们许多人都会发现那是，像我说的那样，一种负担-,它一直笼罩着我们,影响着我们享受生活的能力。

耶鲁公开课 - 死亡课程节选

The amount of marketing, the total marketing burden has gone way up over the years.

营销的开支,最近几年营销费用的总量不断增长

耶鲁公开课 - 关于食物的心理学、生物学和政治学课程节选