Researchers studying the effects of long-term spaceflight often examine the hipbone or backbone.

VOA: special.2009.03.10

But you do, in fact, have to worry about long-term exposure, cyanide poisoning in terms of long-term effects in certain populations that do get the bulk of their carbohydrates from this root, from the root of the Cassava plant.

但是你确实，不得不担心长时间的接触，氰化物的慢性中毒会对,从木薯根中获取大部分,碳水化合物的部分人群产生影响。

麻省理工公开课 - 化学原理课程节选

Long-term use can produce unwanted effects in some people.

VOA: special.2009.04.07

The Mars-500 mission at Moscow's Institute of Biomedical Problems will test the psychological and physical effects of long-term isolation on humans.

VOA: standard.2010.06.02

Also on board is a new exercise machine, which is part of ongoing studies into the effects of long-term space flight on muscle and bone loss in astronauts.

VOA: standard.2010.04.05