How we could take cells that are differentiated to some extent and make them de-differentiate, to go back in the process of differentiation so that they gain more potential.

我们如何把一些已经分化到,一定程度的细胞去分化,使其回到分化之前,重新获得更多的潜能

耶鲁公开课 - 生物医学工程探索课程节选

These signaling proteins play important roles in determining how many cells differentiate down particular pathways and they turn out also to be very useful for treating diseases of those pathways.

这些信号蛋白在决定特定分化路径上,有多少细胞在分化时起着重要作用,且在治疗疾病方面也很有用,同样也是利用这些机制

耶鲁公开课 - 生物医学工程探索课程节选

Well, it would be useful because if I could take cells from the skin, find stem cells in the skin and then de-differentiate them so that they were now capable of becoming liver, or brain, or things that they're not going to become in their normal site, then that could be a very powerful tool for medicine.

这是因为,如果我能取一些皮肤细胞,找一些皮肤干细胞,并将它们去分化,那它们就能分化成肝脏,大脑或其他一些,它们原本分化不出来的细胞,这可以成为一个医学利器

耶鲁公开课 - 生物医学工程探索课程节选