Well, one way to think about is they have more antigen binding sites and so they're going to be more efficient at neutralizing the pathogen on a per-molecule basis than IgG is.

可以这么考虑,因为IgM表面有更多的抗原结合位点,所以相对于IgG,IgM在分子层面上,能够更为有效地与病原体结合

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The IgM is really five IgG-type molecules that are linked together through disulfide bonds, such that their FC portions are all pointing in and their antibody binding portions are all pointing out.

gM是由五个IgG分子组成的,IgG分子之间通过二硫键连接,免疫球蛋白尾部的FC片段都指向内侧,而抗体的抗原结合位点都指向外侧

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The memory cells, which are stimulated, lead to an IgG response and that's why IgG is the antibody of-- that is produced predominantly after the boost, but there is some IgM produced also.

记忆细胞受到刺激之后,可以诱发分泌IgG的应答反应,这也是为什么IgG,是接种疫苗后产生的主要抗体,与此同时也刺激产生了一些IgM

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If you looked later, as the antibody production response matures, some IgG is produced so that in the late period after initial priming you'd have a mixture of IgM and IgG in the blood.

如果你稍后再观察,等到产生抗体的应答趋于成熟后,就会产生一些IgG抗体,在初次免疫的最终阶段,你的血液中有IgM,和IgG两种抗体

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