I mean,how can we say that we want Karzai to do something about his brother's alleged narcotics activities, while apparently the CIA has been paying the same brother?" Former U.S.ambassador to Afghanistan Ronald Neumann tells VOA he believes President Karzai to be a decent man, but points out that he does not have a great deal of actual power outside of Kabul and has to be very careful about alienating some people.

VOA: standard.2009.11.17

And actually, a question that might come up, I just explained, the sodium channel, you might say, well, how do potassium channels work then, because I can understand how you can filter something big out, but how do you filter out something small.

实际上，可能大家会问一个问题，我刚解释过，钠离子通道，你可以说，好吧，那么钾离子通道该如何起作用呢，因为我可以理解你是如何把大东西过滤掉的，但是你如何把小东西过滤掉呢？

麻省理工公开课 - 化学原理课程节选

When you say, "How can I," it might mean simply, "How can you do something?"

当你说，“How can I”，这可能是非常简单地表示，“我怎么样才能做到呢？”

How can I 课堂 - SpeakingMax英语口语达人

And the engineering part of that is sort of the part that I talked about in one slide, when I talked about how do you convert this scientific advance into something that can be delivered all over the world.

这其中的工程部分就是,我曾经在一个幻灯片中讲过的,在我讲到,如何将先进的科学技术成果转化为,可以在世界范围传播的东西

耶鲁公开课 - 生物医学工程探索课程节选

In other words, "How can I" might mean, "I can't do something."

也就是说， "How can I"可能是指“我没法做这事。”

How can I 课堂 - SpeakingMax英语口语达人