By living at home,they will spend That's half the typical cost at a four-year state school, and a fraction of a private university's Adding room and food charges and fees at renowned universities can boost the bill as high as $50,000 a year!

VOA: standard.2009.12.14

Some, like the smallpox vaccine on one exposure generates a very high response that lasts for many years so you don't need a boost.

有一些疫苗,比如接触一次天花疫苗后,人体就能产生高水平的免疫应答,并持续很多年,所以无需再次接种

耶鲁公开课 - 生物医学工程探索课程节选

You have to inject it multiple times because the first blip that you get in immune response is not very high, you have to boost and often you have to boost again in order to get a high enough response to be protected.

你必须得进行多次注射,因为第一次注射,无法使免疫系统产生强烈反应,你得要增强免疫,通常还得再增强一次,以使反应足够强烈,从而起到保护作用

耶鲁公开课 - 生物医学工程探索课程节选