It's a much safer pill and a lot of the difficulties have been worked out in terms of safety and side effects, not all of them, but there are still problems with the Pill.

VOA: standard.2010.05.12

But, as I mentioned briefly in the last class, the notorious difficulties attending this poem seem to have very little to do with Milton's grief over the death of Edward King, which may well not have been all that troubled or complicated.

不过，正如我上节课简要提到的,这首诗的阅读障碍和弥尔顿对爱德华金之死的,悲啜之情并无太大关系，他的哀悼也不是使这首诗艰深复杂的全部原因。

耶鲁公开课 - 弥尔顿课程节选

Do you have any difficulties in studying as a grad student?

你做为一个研究生学习有困难吗？

苦中有乐的学习 - SpeakingMax英语口语达人

Do you have any difficulties in being close with them?

你跟他们的关系变得亲密有困难吗？

有趣的留学生活 - SpeakingMax英语口语达人

Do you have any difficulties in teaching students?

在教学过程中，你遇到过什么困难吗？

布朗克斯的足球教练 - SpeakingMax英语口语达人

Have you met any difficulties in taking the tests?

你在考试中遇到过什么困难吗？

想学习宗教学 - SpeakingMax英语口语达人