It is expected that Democrats will have a tougher challenge in motivating their supporters to get out to vote this year.

VOA: standard.2010.05.04

- Part of the challenge is speed, too, how quickly you can get these answers in terms of getting them in on time.

部分困难也会来自于速度，你多快能做出答案,能否在规定的时间做完。

麻省理工公开课 - 化学原理课程节选

The challenge will be to get legislation on the table that will back up those numbers.

面临的挑战将是进行支持这一目标的立法。

对全球变暖的政策 - SpeakingMax英语口语达人

Demong says that part of the challenge of the ski jump is to get into a good rhythm and stay there.

VOA: standard.2010.01.31

Now the challenge is not just to get the DNA that encodes a gene into a cell, the challenge is to get it into the cell in a form where the cell can use it, can express it and make proteins from it.

现在的问题不仅在于,要将编码基因的DNA转进细胞,还要让它进入细胞之后,能够为细胞所用,能够表达并合成蛋白质

耶鲁公开课 - 生物医学工程探索课程节选

And I think that our challenge and the country's challenge is to get to the point where we can afford the healthcare system that we have in our country."

VOA: standard.2010.02.25

We need to get better at launching ideas." The challenge is convincing the people in member countries, particularly in Western Europe, that what NATO does is important for their future.

VOA: standard.2010.06.11