In addition, doctors now use treatments like gene therapy or remove affected fingers or toes.

VOA: special.2010.07.06

So you made somehow an anti-sense polynucleotide to the insulin gene or some fraction of the insulin gene.

这样你就合成了,胰岛素基因的反义多聚核苷酸链,或者说胰岛素基因的片段

耶鲁公开课 - 生物医学工程探索课程节选

Those animals that you produce are called transgenic animals because they're expressing, usually at high levels, a transgene or a gene that's not normally present in their species.

那么这些小鼠就称为转基因动物,因为转基因动物,通常能高效地,表达转基因,即一个通常不存在于该物种的基因

耶鲁公开课 - 生物医学工程探索课程节选

Gene Fowler wrote that Barrymore was considered an "eighty-six" at one drinking establishment,or bar.

VOA: special.2010.01.08

East Texas is right and now he's punching cows," and that was exactly right, and still I couldn't believe Gene could really have known Slim whom I have been looking for more or less for years.

是在得克萨斯州的东部，但现在他在放牛“,“这可真是太巧了“，但我仍然不能相信,吉恩真的认识细杆，这几年来我一直在找他。

耶鲁公开课 - 1945年后的美国小说课程节选

You're taking advantage of a promoter system, or a gene activation system, that this species knows about because adult animals can make milk.

我们之所以能利用这个启动子系统,或者称之为可以被这一物种识别的,基因活化系统,是因为成年动物可以泌乳

耶鲁公开课 - 生物医学工程探索课程节选

When you think about a gene or a transcript, the messenger RNA copy of a gene, you know that for every sequence of a nucleic acid there's a complimentary sequence.

当你们考虑一段基因或者一个,转录一段基因的mRNA拷贝,你们知道每个核酸序列,都有互补序列

耶鲁公开课 - 生物医学工程探索课程节选

You're taking a normal gene and you're over expressing it or expressing it more abundantly than normal in one particular spot of the body to have an effect.

我们在讨论一个正常基因的过表达,也就是在体内某一点的表达量,大大超过正常水准从而产生疗效

耶鲁公开课 - 生物医学工程探索课程节选

So it's not just knowing what genes or figuring out ways to look at gene expression, it's figuring out how this expression of key genes affects the fate of the individual.

所以我们不仅仅是要了解那些基因能致病,也不仅是要弄明白基因的表达方式,更要搞清楚这种关键基因的表达,如何影响个人命运

耶鲁公开课 - 生物医学工程探索课程节选

That is also an advantage of using them as gene therapy vehicles because they will only infect cells that they are - that they have an affinity for or that they're prone to affect.

非常有利于将其,作为基因治疗的载体使用,因为它们只能感染那些--,它们对之具有亲和性,或者说它们倾向于去感染的细胞

耶鲁公开课 - 生物医学工程探索课程节选

We'll talk about artificial organs and we'll talk about systems biology or thinking about how to acquire information for things like gene chips and use that information to understand what's happening in a complex organism like you.

我们会讨论到人造器官和系统生物学,并探讨如何从基因芯片中得到信息,并利用这些信息了解,人体作为一种复杂有机体的内在变化

耶鲁公开课 - 生物医学工程探索课程节选

Here's an example where we'd like to make insulin, or having the insulin gene would be useful, but if we could take the insulin gene and make many copies of the insulin protein that would be a very useful thing.

例子就是我们人工制造胰岛素,胰岛素基因就很有用,但如果我们可以用胰岛素基因,复制很多胰岛素蛋白,这将会是非常有裨益的一件事

耶鲁公开课 - 生物医学工程探索课程节选

Or what - and often it's not going to be just one gene, it's going to be combinations of genes, and how do you predict the fate of the individual based on all of the genes that you know to be involved in progression of a certain disease.

有时候甚至都不仅仅是一个基因的问题,引发疾病的是一些不同基因的组合,并且怎样基于,导致某种特定疾病的所有基因,来预测一个人未来是否会患这种疾病呢

耶鲁公开课 - 生物医学工程探索课程节选

How did we put our gene fragments into this plasmid DNA in order to make multiple copies of it, or to clone the gene?

如何把基因片段整合到质粒DNA上,来获得大量拷贝,或者说来克隆基因呢

耶鲁公开课 - 生物医学工程探索课程节选

This label is DNA that might be made radioactive or made fluorescent, and it has a base pair sequence that is from some other region of the gene that you're interested in.

这种标签就是具有放射性,或者荧光性的DNA,它有一个取自于,你感兴趣的那段基因上,其他位置的碱基对序列

耶鲁公开课 - 生物医学工程探索课程节选